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Sarcomatoid carcinoma of the gallbladder: a case report
Sarcomatoid carcinoma is a rare type of gallbladder cancer with no specific clinical manifestation. The final diagnosis depends on pathological and immunohistochemical examination. Sarcomatoid carcinoma is characterized by early lymphatic metastasis, rapid progression, a high short-term recurrence r...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323279/ https://www.ncbi.nlm.nih.gov/pubmed/32589472 http://dx.doi.org/10.1177/0300060520935283 |
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author | Shi, Yunfu Chen, Jiabin Chen, Hua Hong, Xiufang |
author_facet | Shi, Yunfu Chen, Jiabin Chen, Hua Hong, Xiufang |
author_sort | Shi, Yunfu |
collection | PubMed |
description | Sarcomatoid carcinoma is a rare type of gallbladder cancer with no specific clinical manifestation. The final diagnosis depends on pathological and immunohistochemical examination. Sarcomatoid carcinoma is characterized by early lymphatic metastasis, rapid progression, a high short-term recurrence rate, and a worse prognosis than adenocarcinoma. This report describes a 60-year-old woman with poorly differentiated adenocarcinoma of the gallbladder. She underwent treatment with chemotherapy and surgery. Palliative surgery was performed for treatment of tumor recurrence in April 2018. Postoperative pathology showed infiltration of poorly differentiated carcinomas, most of which were sarcomatoid. After four cycles of chemotherapy, the disease continued to progress. Anlotinib tablets were given from August 2018 to November 2018 but were then stopped because of gastrointestinal bleeding. The patient died in April 2019. This paper reports the whole process of diagnosis and treatment in this case of gallbladder sarcomatoid carcinoma, thus providing a reference for treatment. |
format | Online Article Text |
id | pubmed-7323279 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-73232792020-07-06 Sarcomatoid carcinoma of the gallbladder: a case report Shi, Yunfu Chen, Jiabin Chen, Hua Hong, Xiufang J Int Med Res Case Report Sarcomatoid carcinoma is a rare type of gallbladder cancer with no specific clinical manifestation. The final diagnosis depends on pathological and immunohistochemical examination. Sarcomatoid carcinoma is characterized by early lymphatic metastasis, rapid progression, a high short-term recurrence rate, and a worse prognosis than adenocarcinoma. This report describes a 60-year-old woman with poorly differentiated adenocarcinoma of the gallbladder. She underwent treatment with chemotherapy and surgery. Palliative surgery was performed for treatment of tumor recurrence in April 2018. Postoperative pathology showed infiltration of poorly differentiated carcinomas, most of which were sarcomatoid. After four cycles of chemotherapy, the disease continued to progress. Anlotinib tablets were given from August 2018 to November 2018 but were then stopped because of gastrointestinal bleeding. The patient died in April 2019. This paper reports the whole process of diagnosis and treatment in this case of gallbladder sarcomatoid carcinoma, thus providing a reference for treatment. SAGE Publications 2020-06-26 /pmc/articles/PMC7323279/ /pubmed/32589472 http://dx.doi.org/10.1177/0300060520935283 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Shi, Yunfu Chen, Jiabin Chen, Hua Hong, Xiufang Sarcomatoid carcinoma of the gallbladder: a case report |
title | Sarcomatoid carcinoma of the gallbladder: a case report |
title_full | Sarcomatoid carcinoma of the gallbladder: a case report |
title_fullStr | Sarcomatoid carcinoma of the gallbladder: a case report |
title_full_unstemmed | Sarcomatoid carcinoma of the gallbladder: a case report |
title_short | Sarcomatoid carcinoma of the gallbladder: a case report |
title_sort | sarcomatoid carcinoma of the gallbladder: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323279/ https://www.ncbi.nlm.nih.gov/pubmed/32589472 http://dx.doi.org/10.1177/0300060520935283 |
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