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DPP-4 inhibition resembles exercise in preventing type 2 diabetes development by inhibiting hepatic protein kinase C(ε) expression in a mouse model of hyperinsulinemia

OBJECTIVE: Interventions for hyperinsulinemia (HINS), an early indicator of type 2 diabetes mellitus (T2DM), can significantly reduce the T2DM risk. This study aims to determine how dipeptidyl peptidase-4 (DPP-4) inhibition prevents HINS progression to T2DM through ameliorating hepatic steatosis. ME...

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Detalles Bibliográficos
Autores principales: Li, Yu-peng, Xiao, Jing, Liang, Xu, Pei, Yu, Han, Xiao-fei, Li, Chen-xi, Tian, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323281/
https://www.ncbi.nlm.nih.gov/pubmed/32588693
http://dx.doi.org/10.1177/0300060520934635