Cargando…
Restoration of physiologic loading modulates engineered intervertebral disc structure and function in an in vivo model
Tissue‐engineered whole disc replacements are an emerging treatment strategy for advanced intervertebral disc degeneration. A challenge facing the translation of tissue‐engineered disc replacement to clinical use are the opposing needs of initial immobilization to advantage integration contrasted wi...
Autores principales: | Gullbrand, Sarah E., Kim, Dong Hwa, Ashinsky, Beth G., Bonnevie, Edward D., Smith, Harvey E., Mauck, Robert L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323465/ https://www.ncbi.nlm.nih.gov/pubmed/32613161 http://dx.doi.org/10.1002/jsp2.1086 |
Ejemplares similares
-
Aberrant mechanosensing in injured intervertebral discs as a result of boundary-constraint disruption and residual-strain loss
por: Bonnevie, Edward D., et al.
Publicado: (2019) -
In Vitro Maturation and In Vivo Integration and Function of an Engineered Cell-Seeded Disc-like Angle Ply Structure (DAPS) for Total Disc Arthroplasty
por: Martin, J. T., et al.
Publicado: (2017) -
Promise, progress, and problems in whole disc tissue engineering
por: Gullbrand, Sarah E., et al.
Publicado: (2018) -
Cell morphology and mechanosensing can be decoupled in fibrous microenvironments and identified using artificial neural networks
por: Bonnevie, Edward D., et al.
Publicado: (2021) -
Development of a standardized histopathology scoring system for intervertebral disc degeneration and regeneration in rabbit models‐An initiative of the ORSspine section
por: Gullbrand, Sarah E., et al.
Publicado: (2021)