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Synonymous variants associated with Alzheimer disease in multiplex families

OBJECTIVE: Synonymous variants can lead to disease; nevertheless, the majority of sequencing studies conducted in Alzheimer disease (AD) only assessed coding variation. METHODS: To detect synonymous variants modulating AD risk, we conducted a whole-genome sequencing study on 67 Caribbean Hispanic (C...

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Detalles Bibliográficos
Autores principales:	Tang, Min, Alaniz, Maria Eugenia, Felsky, Daniel, Vardarajan, Badri, Reyes-Dumeyer, Dolly, Lantigua, Rafael, Medrano, Martin, Bennett, David A., de Jager, Philip L., Mayeux, Richard, Santa-Maria, Ismael, Reitz, Christiane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323483/ https://www.ncbi.nlm.nih.gov/pubmed/32637632 http://dx.doi.org/10.1212/NXG.0000000000000450

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