Ileocolic Intussusception as the Presenting Symptom of Primary Enteric Varicella-Zoster Virus Infection in a 7-Month-Old Infant

Ileocolic intussusception is the invagination of ileum into the colon. In a subset of patients, the disease is caused by mesenteric lymphadenopathy in response to (viral) infection. We present a case of an ileocolic intussusception necessitating surgery in a 7-month-old immunocompetent infant with c...

Descripción completa

Detalles Bibliográficos
Autores principales: Windster, Jonathan D, Ouwendijk, Werner J D, Sloots, Cornelius E J, Verjans, Georges M G M, Verdijk, Robert M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323496/
https://www.ncbi.nlm.nih.gov/pubmed/32232390
http://dx.doi.org/10.1093/infdis/jiaa148
_version_ 1783551779834691584
author Windster, Jonathan D
Ouwendijk, Werner J D
Sloots, Cornelius E J
Verjans, Georges M G M
Verdijk, Robert M
author_facet Windster, Jonathan D
Ouwendijk, Werner J D
Sloots, Cornelius E J
Verjans, Georges M G M
Verdijk, Robert M
author_sort Windster, Jonathan D
collection PubMed
description Ileocolic intussusception is the invagination of ileum into the colon. In a subset of patients, the disease is caused by mesenteric lymphadenopathy in response to (viral) infection. We present a case of an ileocolic intussusception necessitating surgery in a 7-month-old immunocompetent infant with concurrent primary wild-type varicella-zoster virus (VZV) infection, in whom chickenpox rash developed 2 days after surgery. Detailed in situ analyses of resected intestine for specific cell type markers and VZV RNA demonstrated VZV-infected lymphocytes and neurons in the gut wall and in ganglion cells of the myenteric plexus.
format Online
Article
Text
id pubmed-7323496
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-73234962020-07-02 Ileocolic Intussusception as the Presenting Symptom of Primary Enteric Varicella-Zoster Virus Infection in a 7-Month-Old Infant Windster, Jonathan D Ouwendijk, Werner J D Sloots, Cornelius E J Verjans, Georges M G M Verdijk, Robert M J Infect Dis Major Articles and Brief Reports Ileocolic intussusception is the invagination of ileum into the colon. In a subset of patients, the disease is caused by mesenteric lymphadenopathy in response to (viral) infection. We present a case of an ileocolic intussusception necessitating surgery in a 7-month-old immunocompetent infant with concurrent primary wild-type varicella-zoster virus (VZV) infection, in whom chickenpox rash developed 2 days after surgery. Detailed in situ analyses of resected intestine for specific cell type markers and VZV RNA demonstrated VZV-infected lymphocytes and neurons in the gut wall and in ganglion cells of the myenteric plexus. Oxford University Press 2020-07-15 2020-03-31 /pmc/articles/PMC7323496/ /pubmed/32232390 http://dx.doi.org/10.1093/infdis/jiaa148 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Major Articles and Brief Reports
Windster, Jonathan D
Ouwendijk, Werner J D
Sloots, Cornelius E J
Verjans, Georges M G M
Verdijk, Robert M
Ileocolic Intussusception as the Presenting Symptom of Primary Enteric Varicella-Zoster Virus Infection in a 7-Month-Old Infant
title Ileocolic Intussusception as the Presenting Symptom of Primary Enteric Varicella-Zoster Virus Infection in a 7-Month-Old Infant
title_full Ileocolic Intussusception as the Presenting Symptom of Primary Enteric Varicella-Zoster Virus Infection in a 7-Month-Old Infant
title_fullStr Ileocolic Intussusception as the Presenting Symptom of Primary Enteric Varicella-Zoster Virus Infection in a 7-Month-Old Infant
title_full_unstemmed Ileocolic Intussusception as the Presenting Symptom of Primary Enteric Varicella-Zoster Virus Infection in a 7-Month-Old Infant
title_short Ileocolic Intussusception as the Presenting Symptom of Primary Enteric Varicella-Zoster Virus Infection in a 7-Month-Old Infant
title_sort ileocolic intussusception as the presenting symptom of primary enteric varicella-zoster virus infection in a 7-month-old infant
topic Major Articles and Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323496/
https://www.ncbi.nlm.nih.gov/pubmed/32232390
http://dx.doi.org/10.1093/infdis/jiaa148
work_keys_str_mv AT windsterjonathand ileocolicintussusceptionasthepresentingsymptomofprimaryentericvaricellazostervirusinfectionina7montholdinfant
AT ouwendijkwernerjd ileocolicintussusceptionasthepresentingsymptomofprimaryentericvaricellazostervirusinfectionina7montholdinfant
AT slootscorneliusej ileocolicintussusceptionasthepresentingsymptomofprimaryentericvaricellazostervirusinfectionina7montholdinfant
AT verjansgeorgesmgm ileocolicintussusceptionasthepresentingsymptomofprimaryentericvaricellazostervirusinfectionina7montholdinfant
AT verdijkrobertm ileocolicintussusceptionasthepresentingsymptomofprimaryentericvaricellazostervirusinfectionina7montholdinfant

Ejemplares similares