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Assessing neuraxial microstructural changes in a transgenic mouse model of early stage Amyotrophic Lateral Sclerosis by ultra‐high field MRI and diffusion tensor metrics

OBJECTIVE: Cell structural changes are one of the main features observed during the development of amyotrophic lateral sclerosis (ALS). In this work, we propose the use of diffusion tensor imaging (DTI) metrics to assess specific ultrastructural changes in the central nervous system during the early...

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Detalles Bibliográficos
Autores principales: Gatto, Rodolfo G., Weissmann, Carina, Amin, Manish, Finkielsztein, Ariel, Sumagin, Ronen, Mareci, Thomas H., Uchitel, Osvaldo D., Magin, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323706/
https://www.ncbi.nlm.nih.gov/pubmed/32613171
http://dx.doi.org/10.1002/ame2.12112