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Lidocaine Suppresses Cell Proliferation and Aerobic Glycolysis by Regulating circHOMER1/miR-138-5p/HEY1 Axis in Colorectal Cancer

BACKGROUND: Increasing evidence has uncovered the anticancer activity of lidocaine in many cancers. However, the role and the underlying molecular mechanism of lidocaine in colorectal cancer (CRC) remain poorly understood. MATERIALS AND METHODS: Cell viability and apoptosis were measured by cell cou...

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Detalles Bibliográficos
Autores principales: Du, Juan, Zhang, Liying, Ma, Hongzhong, Wang, Yang, Wang, Pengpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323806/
https://www.ncbi.nlm.nih.gov/pubmed/32612388
http://dx.doi.org/10.2147/CMAR.S244973