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Outbreak analysis with a logistic growth model shows COVID-19 suppression dynamics in China

China reported a major outbreak of a novel coronavirus, SARS-CoV2, from mid-January till mid-March 2020. We review the epidemic virus growth and decline curves in China using a phenomenological logistic growth model to summarize the outbreak dynamics using three parameters that characterize the epid...

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Autores principales: Zou, Yi, Pan, Stephen, Zhao, Peng, Han, Lei, Wang, Xiaoxiang, Hemerik, Lia, Knops, Johannes, van der Werf, Wopke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323941/
https://www.ncbi.nlm.nih.gov/pubmed/32598342
http://dx.doi.org/10.1371/journal.pone.0235247
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author Zou, Yi
Pan, Stephen
Zhao, Peng
Han, Lei
Wang, Xiaoxiang
Hemerik, Lia
Knops, Johannes
van der Werf, Wopke
author_facet Zou, Yi
Pan, Stephen
Zhao, Peng
Han, Lei
Wang, Xiaoxiang
Hemerik, Lia
Knops, Johannes
van der Werf, Wopke
author_sort Zou, Yi
collection PubMed
description China reported a major outbreak of a novel coronavirus, SARS-CoV2, from mid-January till mid-March 2020. We review the epidemic virus growth and decline curves in China using a phenomenological logistic growth model to summarize the outbreak dynamics using three parameters that characterize the epidemic’s timing, rate and peak. During the initial phase, the number of virus cases doubled every 2.7 days (range 2.2–4.4 across provinces). The rate of increase in the number of reported cases peaked approximately 10 days after suppression measures were started on 23–25 January 2020. The peak in the number of reported sick cases occurred on average 18 days after the start of suppression measures. From the time of starting measures till the peak, the number of cases increased by a factor 39 in the province Hubei, and by a factor 9.5 for all of China (range: 6.2–20.4 in the other provinces). Complete suppression took up to 2 months (range: 23-57d.), during which period severe restrictions, social distancing measures, testing and isolation of cases were in place. The suppression of the disease in China has been successful, demonstrating that suppression is a viable strategy to contain SARS-CoV2.
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spelling pubmed-73239412020-07-08 Outbreak analysis with a logistic growth model shows COVID-19 suppression dynamics in China Zou, Yi Pan, Stephen Zhao, Peng Han, Lei Wang, Xiaoxiang Hemerik, Lia Knops, Johannes van der Werf, Wopke PLoS One Research Article China reported a major outbreak of a novel coronavirus, SARS-CoV2, from mid-January till mid-March 2020. We review the epidemic virus growth and decline curves in China using a phenomenological logistic growth model to summarize the outbreak dynamics using three parameters that characterize the epidemic’s timing, rate and peak. During the initial phase, the number of virus cases doubled every 2.7 days (range 2.2–4.4 across provinces). The rate of increase in the number of reported cases peaked approximately 10 days after suppression measures were started on 23–25 January 2020. The peak in the number of reported sick cases occurred on average 18 days after the start of suppression measures. From the time of starting measures till the peak, the number of cases increased by a factor 39 in the province Hubei, and by a factor 9.5 for all of China (range: 6.2–20.4 in the other provinces). Complete suppression took up to 2 months (range: 23-57d.), during which period severe restrictions, social distancing measures, testing and isolation of cases were in place. The suppression of the disease in China has been successful, demonstrating that suppression is a viable strategy to contain SARS-CoV2. Public Library of Science 2020-06-29 /pmc/articles/PMC7323941/ /pubmed/32598342 http://dx.doi.org/10.1371/journal.pone.0235247 Text en © 2020 Zou et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Zou, Yi
Pan, Stephen
Zhao, Peng
Han, Lei
Wang, Xiaoxiang
Hemerik, Lia
Knops, Johannes
van der Werf, Wopke
Outbreak analysis with a logistic growth model shows COVID-19 suppression dynamics in China
title Outbreak analysis with a logistic growth model shows COVID-19 suppression dynamics in China
title_full Outbreak analysis with a logistic growth model shows COVID-19 suppression dynamics in China
title_fullStr Outbreak analysis with a logistic growth model shows COVID-19 suppression dynamics in China
title_full_unstemmed Outbreak analysis with a logistic growth model shows COVID-19 suppression dynamics in China
title_short Outbreak analysis with a logistic growth model shows COVID-19 suppression dynamics in China
title_sort outbreak analysis with a logistic growth model shows covid-19 suppression dynamics in china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323941/
https://www.ncbi.nlm.nih.gov/pubmed/32598342
http://dx.doi.org/10.1371/journal.pone.0235247
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