Prospective Evaluation of Effect of Metformin on Activation of AMP-activated Protein Kinase (AMPK) and Disease Control in a Sub-group Analysis of Patients with GI Malignancies

BACKGROUND: Observational studies have demonstrated association of metformin with reduced cancer incidence and mortality in multiple cancer types, including gastrointestinal (GI) malignancies. Anti-neoplastic effects of metformin are believed through many mechanisms including activation of AMP-activ...

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Detalles Bibliográficos
Autores principales: Godara, Amandeep, Siddiqui, Nauman S., Hachem, Hilal, Tsichlis, Philip N., Martell, Robert E., Saif, Muhammad Wasif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323959/
https://www.ncbi.nlm.nih.gov/pubmed/32601620
http://dx.doi.org/10.33696/Signaling.1.008

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