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Ebola virus glycoprotein stimulates IL-18–dependent natural killer cell responses

BACKGROUND: NK cells are activated by innate cytokines and viral ligands to kill virus-infected cells. These functions are enhanced during secondary immune responses and after vaccination by synergy with effector T cells and virus-specific antibodies. In human Ebola virus infection, clinical outcome...

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Detalles Bibliográficos
Autores principales: Wagstaffe, Helen R., Clutterbuck, Elizabeth A., Bockstal, Viki, Stoop, Jeroen N., Luhn, Kerstin, Douoguih, Macaya, Shukarev, Georgi, Snape, Matthew D., Pollard, Andrew J., Riley, Eleanor M., Goodier, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324188/
https://www.ncbi.nlm.nih.gov/pubmed/32315287
http://dx.doi.org/10.1172/JCI132438