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Novel phosphatidylinositol 4-kinases III beta (PI4KIIIβ) inhibitors discovered by virtual screening using free energy models

Herein, the LASSBio Chemical Library is presented as a valuable source of compounds for screening to identify hits suitable for subsequent hit-to-lead optimization stages. A feature of the LASSBio Chemical Library worth highlighting is the fact that it is a smart library designed by medicinal chemis...

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Detalles Bibliográficos
Autores principales:	Colodette, Natalie M., Franco, Lucas S., Maia, Rodolfo C., Fokoue, Harold H., Sant’Anna, Carlos Mauricio R., Barreiro, Eliezer J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324290/ https://www.ncbi.nlm.nih.gov/pubmed/32601839 http://dx.doi.org/10.1007/s10822-020-00327-9

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