Cargando…

Cytoplasmic versus nuclear THR alpha expression determines survival of ovarian cancer patients

PURPOSE: Thyroid hormone receptors (THR) have manifold functions and are involved in the carcinogenesis of several tumor types. Within this study, we aimed to investigate the expression pattern (nuclear versus cytoplasmic) of the THR alpha and its impact on patients survival in ovarian cancer (OvCa)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ditsch, Nina, Heublein, Sabine, Jeschke, Udo, Sattler, Cornelia, Kuhn, Christina, Hester, Anna, Czogalla, Bastian, Trillsch, Fabian, Mahner, Sven, Engel, Jutta, Mayr, Doris, Schmoeckel, Elisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Article – Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324415/ https://www.ncbi.nlm.nih.gov/pubmed/32533406 http://dx.doi.org/10.1007/s00432-020-03241-7

Ejemplares similares

Subcellular Distribution of Thyroid Hormone Receptor Beta in Ovarian Cancer
por: Heublein, Sabine, et al.
Publicado: (2022)

Cytoplasmic VDR expression as an independent risk factor for ovarian cancer
por: Czogalla, Bastian, et al.
Publicado: (2020)

The G-Protein-Coupled Estrogen Receptor (GPER) Regulates Trimethylation of Histone H3 at Lysine 4 and Represses Migration and Proliferation of Ovarian Cancer Cells In Vitro
por: Han, Nan, et al.
Publicado: (2021)

Breast adipose tissue macrophages (BATMs) have a stronger correlation with breast cancer survival than breast tumor stroma macrophages (BTSMs)
por: Lin, Lili, et al.
Publicado: (2021)

H3K4me3 Is a Potential Mediator for Antiproliferative Effects of Calcitriol (1α,25(OH)2D3) in Ovarian Cancer Biology
por: Han, Nan, et al.
Publicado: (2020)

PD-L1 expression and survival in p16-negative and -positive squamous cell carcinomas of the vulva
por: Czogalla, Bastian, et al.
Publicado: (2020)

Interaction of ERα and NRF2 Impacts Survival in Ovarian Cancer Patients
por: Czogalla, Bastian, et al.
Publicado: (2018)

Nuclear Enolase-1/ MBP-1 expression and its association with the Wnt signaling in epithelial ovarian cancer
por: Czogalla, Bastian, et al.
Publicado: (2020)

Potential Interplay of the Gatipotuzumab Epitope TA-MUC1 and Estrogen Receptors in Ovarian Cancer
por: Heublein, Sabine, et al.
Publicado: (2019)

Correlation of NRF2 and progesterone receptor and its effects on ovarian cancer biology
por: Czogalla, Bastian, et al.
Publicado: (2019)

First Evidence for a Role of Siglec-8 in Breast Cancer
por: Trebo, Anna, et al.
Publicado: (2021)

Potential of platinum-resensitization by Wnt signaling modulators as treatment approach for epithelial ovarian cancer
por: Kaltofen, Till, et al.
Publicado: (2020)

Extracapsular Lymph Node Involvement in Ovarian Carcinoma
por: Heublein, Sabine, et al.
Publicado: (2019)

KLF11 is an independent negative prognostic factor for breast cancer from a cohort study and induces proliferation and inhibits apoptosis in vitro
por: Lin, Lili, et al.
Publicado: (2023)

Cytoplasmic LXR expression is an independent marker of poor prognosis for patients with early stage primary breast cancer
por: Shao, Wanting, et al.
Publicado: (2021)

Correlation of the Aryl Hydrocarbon Receptor with FSHR in Ovarian Cancer Patients
por: Deuster, Eileen, et al.
Publicado: (2019)

M2 Macrophages Infiltrating Epithelial Ovarian Cancer Express MDR1: A Feature That May Account for the Poor Prognosis
por: Badmann, Susann, et al.
Publicado: (2020)

AKR1C1/2 inhibition by MPA sensitizes platinum resistant ovarian cancer towards carboplatin
por: Badmann, Susann, et al.
Publicado: (2022)

The role of resveratrol, Sirtuin1 and RXRα as prognostic markers in ovarian cancer
por: Chen, Fangfang, et al.
Publicado: (2021)

The Platelet-Activating Factor Receptor’s Association with the Outcome of Ovarian Cancer Patients and Its Experimental Inhibition by Rupatadine
por: Deuster, Eileen, et al.
Publicado: (2021)

G Protein-Coupled Estrogen Receptor Correlates With Dkk2 Expression and Has Prognostic Impact in Ovarian Cancer Patients
por: Fraungruber, Patricia, et al.
Publicado: (2021)

High Galectin-7 and Low Galectin-8 Expression and the Combination of both are Negative Prognosticators for Breast Cancer Patients
por: Trebo, Anna, et al.
Publicado: (2020)

Expression of H3K4me3 and H3K9ac in breast cancer
por: Berger, Luisa, et al.
Publicado: (2020)

Platelet-Activating Factor Acetylhydrolase Expression in BRCA1 Mutant Ovarian Cancer as a Protective Factor and Potential Negative Regulator of the Wnt Signaling Pathway
por: Liao, Yue, et al.
Publicado: (2021)

PLA2G7/PAF-AH as Potential Negative Regulator of the Wnt Signaling Pathway Mediates Protective Effects in BRCA1 Mutant Breast Cancer
por: Liao, Yue, et al.
Publicado: (2023)

Blood group antigens SLeX, SLeA, and LeY as prognostic markers in endometrial cancer
por: Kolben, Thomas, et al.
Publicado: (2022)

Sirtuin1 expression and survival in endometrial and clear-cell uterine cancer
por: Beyer, Susanne, et al.
Publicado: (2020)

Galectin-8 and -9 as prognostic factors for cervical cancer
por: Beyer, Susanne, et al.
Publicado: (2022)

Cytoplasmic and Nuclear Forms of Thyroid Hormone Receptor β1 Are Inversely Associated with Survival in Primary Breast Cancer
por: Shao, Wanting, et al.
Publicado: (2020)

Cytoplasmic PPARγ is a marker of poor prognosis in patients with Cox-1 negative primary breast cancers
por: Shao, Wanting, et al.
Publicado: (2020)

Actin Beta-Like 2 as a New Mediator of Proliferation and Migration in Epithelial Ovarian Cancer
por: Topalov, Nicole Elisabeth, et al.
Publicado: (2021)

Vitamin D receptor, Retinoid X receptor and peroxisome proliferator-activated receptor γ are overexpressed in BRCA1 mutated breast cancer and predict prognosis
por: Heublein, Sabine, et al.
Publicado: (2017)

EP3 receptor antagonist L798,106 reduces proliferation and migration of SK-BR-3 breast cancer cells
por: Hester, Anna, et al.
Publicado: (2019)

Lysine-specific histone demethylase 1A (LSD1) in cervical cancer
por: Beilner, Daniel, et al.
Publicado: (2020)

β-arrestin 2 Is a Prognostic Factor for Survival of Ovarian Cancer Patients Upregulating Cell Proliferation
por: Czogalla, Bastian, et al.
Publicado: (2020)

Combined COX-2/PPARγ Expression as Independent Negative Prognosticator for Vulvar Cancer Patients
por: Ansorge, Nadine, et al.
Publicado: (2021)

Thyroid Hormone Receptors Predict Prognosis in BRCA1 Associated Breast Cancer in Opposing Ways
por: Heublein, Sabine, et al.
Publicado: (2015)

Overall Survival of Ovarian Cancer Patients Is Determined by Expression of Galectins-8 and -9
por: Schulz, Heiko, et al.
Publicado: (2018)

Galectins-1, -3, and -7 Are Prognostic Markers for Survival of Ovarian Cancer Patients †
por: Schulz, Heiko, et al.
Publicado: (2017)

Development and Validation of a Novel 11-Gene Prognostic Model for Serous Ovarian Carcinomas Based on Lipid Metabolism Expression Profile
por: Zheng, Mingjun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qm0v19eepa2n5ei4lp84hqvfij