A Generic Procedure for the Isolation of pH- and Magnesium-Responsive Chicken scFvs for Downstream Purification of Human Antibodies

Affinity chromatography provides an excellent platform for protein purification, which is a key step in the large scale downstream processing of therapeutic monoclonal antibodies (Mabs). Protein A chromatography constitutes the gold standard for Mab purification. However, the required acidic conditi...

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Detalles Bibliográficos
Autores principales: Hinz, Steffen C., Elter, Adrian, Rammo, Oliver, Schwämmle, Achim, Ali, Ataurehman, Zielonka, Stefan, Herget, Thomas, Kolmar, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324474/
https://www.ncbi.nlm.nih.gov/pubmed/32656201
http://dx.doi.org/10.3389/fbioe.2020.00688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324474/
https://www.ncbi.nlm.nih.gov/pubmed/32656201
http://dx.doi.org/10.3389/fbioe.2020.00688

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