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MicroRNA-200a Inhibits Inflammation and Atherosclerotic Lesion Formation by Disrupting EZH2-Mediated Methylation of STAT3

Endothelial inflammation and dysfunction are critical to the process of atherosclerosis. Emerging evidence demonstrates that upregulation of miR-200a reduces VCAM-1 expression and prevents monocytic cell adhesion onto the aortic endothelium. However, limited information is available about the role o...

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Detalles Bibliográficos
Autores principales: Wang, Jinpeng, Li, Ping, Xu, Xiaofei, Zhang, Beilin, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324475/
https://www.ncbi.nlm.nih.gov/pubmed/32655542
http://dx.doi.org/10.3389/fimmu.2020.00907