eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled

The Wingless/Int1 (Wnt) signaling system plays multiple, essential roles in embryonic development, tissue homeostasis, and human diseases. Although many of the underlying signaling mechanisms are becoming clearer, the binding mode, kinetics, and selectivity of 19 mammalian WNTs to their receptors of...

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Detalles Bibliográficos
Autores principales: Wesslowski, Janine, Kozielewicz, Pawel, Wang, Xianxian, Cui, Haijun, Schihada, Hannes, Kranz, Dominique, Karuna M, Pradhipa, Levkin, Pavel, Gross, Julia Christina, Boutros, Michael, Schulte, Gunnar, Davidson, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324525/
https://www.ncbi.nlm.nih.gov/pubmed/32381507
http://dx.doi.org/10.1074/jbc.RA120.012892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324525/
https://www.ncbi.nlm.nih.gov/pubmed/32381507
http://dx.doi.org/10.1074/jbc.RA120.012892

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