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Drosophila as a Model Organism in Host–Pathogen Interaction Studies

Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host–pathogen interactions and...

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Detalles Bibliográficos
Autores principales: Younes, Salma, Al-Sulaiti, Asma, Nasser, Elham Abdulwahab Ahmed, Najjar, Hoda, Kamareddine, Layla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324642/
https://www.ncbi.nlm.nih.gov/pubmed/32656090
http://dx.doi.org/10.3389/fcimb.2020.00214
Descripción
Sumario:Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host–pathogen interactions and identifying chief factors involved in host defense and pathogen virulence in Drosophila serves as a foundation to establish novel strategies for infectious disease prevention and control in higher organisms, including humans.