Drosophila as a Model Organism in Host–Pathogen Interaction Studies

Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host–pathogen interactions and...

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Autores principales: Younes, Salma, Al-Sulaiti, Asma, Nasser, Elham Abdulwahab Ahmed, Najjar, Hoda, Kamareddine, Layla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324642/
https://www.ncbi.nlm.nih.gov/pubmed/32656090
http://dx.doi.org/10.3389/fcimb.2020.00214
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author Younes, Salma
Al-Sulaiti, Asma
Nasser, Elham Abdulwahab Ahmed
Najjar, Hoda
Kamareddine, Layla
author_facet Younes, Salma
Al-Sulaiti, Asma
Nasser, Elham Abdulwahab Ahmed
Najjar, Hoda
Kamareddine, Layla
author_sort Younes, Salma
collection PubMed
description Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host–pathogen interactions and identifying chief factors involved in host defense and pathogen virulence in Drosophila serves as a foundation to establish novel strategies for infectious disease prevention and control in higher organisms, including humans.
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spelling pubmed-73246422020-07-10 Drosophila as a Model Organism in Host–Pathogen Interaction Studies Younes, Salma Al-Sulaiti, Asma Nasser, Elham Abdulwahab Ahmed Najjar, Hoda Kamareddine, Layla Front Cell Infect Microbiol Cellular and Infection Microbiology Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host–pathogen interactions and identifying chief factors involved in host defense and pathogen virulence in Drosophila serves as a foundation to establish novel strategies for infectious disease prevention and control in higher organisms, including humans. Frontiers Media S.A. 2020-06-23 /pmc/articles/PMC7324642/ /pubmed/32656090 http://dx.doi.org/10.3389/fcimb.2020.00214 Text en Copyright © 2020 Younes, Al-Sulaiti, Nasser, Najjar and Kamareddine. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Younes, Salma
Al-Sulaiti, Asma
Nasser, Elham Abdulwahab Ahmed
Najjar, Hoda
Kamareddine, Layla
Drosophila as a Model Organism in Host–Pathogen Interaction Studies
title Drosophila as a Model Organism in Host–Pathogen Interaction Studies
title_full Drosophila as a Model Organism in Host–Pathogen Interaction Studies
title_fullStr Drosophila as a Model Organism in Host–Pathogen Interaction Studies
title_full_unstemmed Drosophila as a Model Organism in Host–Pathogen Interaction Studies
title_short Drosophila as a Model Organism in Host–Pathogen Interaction Studies
title_sort drosophila as a model organism in host–pathogen interaction studies
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324642/
https://www.ncbi.nlm.nih.gov/pubmed/32656090
http://dx.doi.org/10.3389/fcimb.2020.00214
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