Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages

CDC and WHO guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis only recommend synthetic fiber swabs for nasopharyngeal (NP) sampling. We show that cotton-tipped plastic swabs do not inhibit PCR and have equivalent performance to rayon swabs. Cotton-tipped plastic s...

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Autores principales: Freire-Paspuel, Byron, Vega-Mariño, Patricio, Velez, Alberto, Castillo, Paulina, Gomez-Santos, Eliana Elizabeth, Cruz, Marilyn, Garcia-Bereguiain, Miguel Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324669/
https://www.ncbi.nlm.nih.gov/pubmed/32656101
http://dx.doi.org/10.3389/fcimb.2020.00356
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author Freire-Paspuel, Byron
Vega-Mariño, Patricio
Velez, Alberto
Castillo, Paulina
Gomez-Santos, Eliana Elizabeth
Cruz, Marilyn
Garcia-Bereguiain, Miguel Angel
author_facet Freire-Paspuel, Byron
Vega-Mariño, Patricio
Velez, Alberto
Castillo, Paulina
Gomez-Santos, Eliana Elizabeth
Cruz, Marilyn
Garcia-Bereguiain, Miguel Angel
author_sort Freire-Paspuel, Byron
collection PubMed
description CDC and WHO guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis only recommend synthetic fiber swabs for nasopharyngeal (NP) sampling. We show that cotton-tipped plastic swabs do not inhibit PCR and have equivalent performance to rayon swabs. Cotton-tipped plastic swabs are massively produced worldwide and would prevent swab supply shortages under the current high SARS-CoV-2 testing demands, particularly in developing countries.
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spelling pubmed-73246692020-07-10 Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages Freire-Paspuel, Byron Vega-Mariño, Patricio Velez, Alberto Castillo, Paulina Gomez-Santos, Eliana Elizabeth Cruz, Marilyn Garcia-Bereguiain, Miguel Angel Front Cell Infect Microbiol Cellular and Infection Microbiology CDC and WHO guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis only recommend synthetic fiber swabs for nasopharyngeal (NP) sampling. We show that cotton-tipped plastic swabs do not inhibit PCR and have equivalent performance to rayon swabs. Cotton-tipped plastic swabs are massively produced worldwide and would prevent swab supply shortages under the current high SARS-CoV-2 testing demands, particularly in developing countries. Frontiers Media S.A. 2020-06-23 /pmc/articles/PMC7324669/ /pubmed/32656101 http://dx.doi.org/10.3389/fcimb.2020.00356 Text en Copyright © 2020 Freire-Paspuel, Vega-Mariño, Velez, Castillo, Gomez-Santos, Cruz and Garcia-Bereguiain. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Freire-Paspuel, Byron
Vega-Mariño, Patricio
Velez, Alberto
Castillo, Paulina
Gomez-Santos, Eliana Elizabeth
Cruz, Marilyn
Garcia-Bereguiain, Miguel Angel
Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages
title Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages
title_full Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages
title_fullStr Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages
title_full_unstemmed Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages
title_short Cotton-Tipped Plastic Swabs for SARS-CoV-2 RT-qPCR Diagnosis to Prevent Supply Shortages
title_sort cotton-tipped plastic swabs for sars-cov-2 rt-qpcr diagnosis to prevent supply shortages
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324669/
https://www.ncbi.nlm.nih.gov/pubmed/32656101
http://dx.doi.org/10.3389/fcimb.2020.00356
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