Interleukin (IL)-21 Promotes the Differentiation of IgA-Producing Plasma Cells in Porcine Peyer's Patches via the JAK-STAT Signaling Pathway

Secretory IgA is critical to prevent the invasion of pathogens via mucosa. However, the key factors and the mechanisms of IgA generation in the porcine gut are not well-understood. In this study, a panel of factors, including BAFF, APRIL, CD40L, TGF-β1, IL-6, IL-10, IL-17A, and IL-21, were employed...

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Detalles Bibliográficos
Autores principales: Liu, Guo, Wang, Bin, Chen, Qingbo, Li, Yang, Li, Baoyu, Yang, Ning, Yang, Shanshan, Geng, Shuxian, Liu, Guangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324671/
https://www.ncbi.nlm.nih.gov/pubmed/32655571
http://dx.doi.org/10.3389/fimmu.2020.01303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324671/
https://www.ncbi.nlm.nih.gov/pubmed/32655571
http://dx.doi.org/10.3389/fimmu.2020.01303

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