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Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles
BACKGROUND: To treat multiple targets separated in the craniocaudal direction within a short time, we invented a new technique using multiple static‐port tomotherapy with the dynamic‐jaw mode and named it the pseudo‐DJDC (pDJDC) technique. We compared the pDJDC plans and helical tomotherapy plans us...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324698/ https://www.ncbi.nlm.nih.gov/pubmed/32250015 http://dx.doi.org/10.1002/acm2.12874 |
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author | Manabe, Yoshihiko Shibamoto, Yuta Murai, Taro Torii, Akira Niwa, Masanari Kondo, Takuhito Okazaki, Dai Sugie, Chikao |
author_facet | Manabe, Yoshihiko Shibamoto, Yuta Murai, Taro Torii, Akira Niwa, Masanari Kondo, Takuhito Okazaki, Dai Sugie, Chikao |
author_sort | Manabe, Yoshihiko |
collection | PubMed |
description | BACKGROUND: To treat multiple targets separated in the craniocaudal direction within a short time, we invented a new technique using multiple static‐port tomotherapy with the dynamic‐jaw mode and named it the pseudo‐DJDC (pDJDC) technique. We compared the pDJDC plans and helical tomotherapy plans using the dynamic‐jaw mode (HDJ) for multiple targets. In the pDJDC plans, we used a beam set with 2–7 ports to the targets at the same level in the craniocaudal direction, and employed another beam set for other targets using different port angles (9–12 angles in total). METHODS: In seven patients, two plans using the pDJDC and HDJ techniques were compared. For multiple targets (n = 2–6), 20–60 Gy in 2‐ to 7.5‐Gy fractions were prescribed for the planning target volumes at D50%. The conformity index, uniformity index (D5%/D95%), dose distribution in the lung, and treatment time were evaluated. RESULTS: The median conformity index of all seven patients was 3.0 for the pDJDC plans and 2.4 for the HDJ plans (P = 0.031). The median uniformity indices of the planning target volume (n = 25) for the two plans were 1.048 and 1.057, respectively (P = 0.10). For five patients with thoracic targets, the median mean lung doses were 2.6 Gy and 2.4 Gy, respectively (P = 0.63). The median V5Gy and V20Gy of the lungs in the five patients were 11.8% and 8.5% (P = 0.63), and 1.6% and 2.1% (P = 0.31), respectively. The pDJDC plans reduced the treatment time by 48% compared to the HDJ plans (median: 462 and 884 sec, respectively, P = 0.031). CONCLUSION: The pDJDC technique allows treatment of multiple targets in almost half the time of the HDJ technique. The pDJDC plans were comparable to the HDJ plans in dose distribution, although the conformity index deteriorated. |
format | Online Article Text |
id | pubmed-7324698 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73246982020-07-01 Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles Manabe, Yoshihiko Shibamoto, Yuta Murai, Taro Torii, Akira Niwa, Masanari Kondo, Takuhito Okazaki, Dai Sugie, Chikao J Appl Clin Med Phys Radiation Oncology Physics BACKGROUND: To treat multiple targets separated in the craniocaudal direction within a short time, we invented a new technique using multiple static‐port tomotherapy with the dynamic‐jaw mode and named it the pseudo‐DJDC (pDJDC) technique. We compared the pDJDC plans and helical tomotherapy plans using the dynamic‐jaw mode (HDJ) for multiple targets. In the pDJDC plans, we used a beam set with 2–7 ports to the targets at the same level in the craniocaudal direction, and employed another beam set for other targets using different port angles (9–12 angles in total). METHODS: In seven patients, two plans using the pDJDC and HDJ techniques were compared. For multiple targets (n = 2–6), 20–60 Gy in 2‐ to 7.5‐Gy fractions were prescribed for the planning target volumes at D50%. The conformity index, uniformity index (D5%/D95%), dose distribution in the lung, and treatment time were evaluated. RESULTS: The median conformity index of all seven patients was 3.0 for the pDJDC plans and 2.4 for the HDJ plans (P = 0.031). The median uniformity indices of the planning target volume (n = 25) for the two plans were 1.048 and 1.057, respectively (P = 0.10). For five patients with thoracic targets, the median mean lung doses were 2.6 Gy and 2.4 Gy, respectively (P = 0.63). The median V5Gy and V20Gy of the lungs in the five patients were 11.8% and 8.5% (P = 0.63), and 1.6% and 2.1% (P = 0.31), respectively. The pDJDC plans reduced the treatment time by 48% compared to the HDJ plans (median: 462 and 884 sec, respectively, P = 0.031). CONCLUSION: The pDJDC technique allows treatment of multiple targets in almost half the time of the HDJ technique. The pDJDC plans were comparable to the HDJ plans in dose distribution, although the conformity index deteriorated. John Wiley and Sons Inc. 2020-04-06 /pmc/articles/PMC7324698/ /pubmed/32250015 http://dx.doi.org/10.1002/acm2.12874 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Manabe, Yoshihiko Shibamoto, Yuta Murai, Taro Torii, Akira Niwa, Masanari Kondo, Takuhito Okazaki, Dai Sugie, Chikao Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles |
title | Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles |
title_full | Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles |
title_fullStr | Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles |
title_full_unstemmed | Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles |
title_short | Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles |
title_sort | intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324698/ https://www.ncbi.nlm.nih.gov/pubmed/32250015 http://dx.doi.org/10.1002/acm2.12874 |
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