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Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles

BACKGROUND: To treat multiple targets separated in the craniocaudal direction within a short time, we invented a new technique using multiple static‐port tomotherapy with the dynamic‐jaw mode and named it the pseudo‐DJDC (pDJDC) technique. We compared the pDJDC plans and helical tomotherapy plans us...

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Autores principales: Manabe, Yoshihiko, Shibamoto, Yuta, Murai, Taro, Torii, Akira, Niwa, Masanari, Kondo, Takuhito, Okazaki, Dai, Sugie, Chikao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324698/
https://www.ncbi.nlm.nih.gov/pubmed/32250015
http://dx.doi.org/10.1002/acm2.12874
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author Manabe, Yoshihiko
Shibamoto, Yuta
Murai, Taro
Torii, Akira
Niwa, Masanari
Kondo, Takuhito
Okazaki, Dai
Sugie, Chikao
author_facet Manabe, Yoshihiko
Shibamoto, Yuta
Murai, Taro
Torii, Akira
Niwa, Masanari
Kondo, Takuhito
Okazaki, Dai
Sugie, Chikao
author_sort Manabe, Yoshihiko
collection PubMed
description BACKGROUND: To treat multiple targets separated in the craniocaudal direction within a short time, we invented a new technique using multiple static‐port tomotherapy with the dynamic‐jaw mode and named it the pseudo‐DJDC (pDJDC) technique. We compared the pDJDC plans and helical tomotherapy plans using the dynamic‐jaw mode (HDJ) for multiple targets. In the pDJDC plans, we used a beam set with 2–7 ports to the targets at the same level in the craniocaudal direction, and employed another beam set for other targets using different port angles (9–12 angles in total). METHODS: In seven patients, two plans using the pDJDC and HDJ techniques were compared. For multiple targets (n = 2–6), 20–60 Gy in 2‐ to 7.5‐Gy fractions were prescribed for the planning target volumes at D50%. The conformity index, uniformity index (D5%/D95%), dose distribution in the lung, and treatment time were evaluated. RESULTS: The median conformity index of all seven patients was 3.0 for the pDJDC plans and 2.4 for the HDJ plans (P = 0.031). The median uniformity indices of the planning target volume (n = 25) for the two plans were 1.048 and 1.057, respectively (P = 0.10). For five patients with thoracic targets, the median mean lung doses were 2.6 Gy and 2.4 Gy, respectively (P = 0.63). The median V5Gy and V20Gy of the lungs in the five patients were 11.8% and 8.5% (P = 0.63), and 1.6% and 2.1% (P = 0.31), respectively. The pDJDC plans reduced the treatment time by 48% compared to the HDJ plans (median: 462 and 884 sec, respectively, P = 0.031). CONCLUSION: The pDJDC technique allows treatment of multiple targets in almost half the time of the HDJ technique. The pDJDC plans were comparable to the HDJ plans in dose distribution, although the conformity index deteriorated.
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spelling pubmed-73246982020-07-01 Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles Manabe, Yoshihiko Shibamoto, Yuta Murai, Taro Torii, Akira Niwa, Masanari Kondo, Takuhito Okazaki, Dai Sugie, Chikao J Appl Clin Med Phys Radiation Oncology Physics BACKGROUND: To treat multiple targets separated in the craniocaudal direction within a short time, we invented a new technique using multiple static‐port tomotherapy with the dynamic‐jaw mode and named it the pseudo‐DJDC (pDJDC) technique. We compared the pDJDC plans and helical tomotherapy plans using the dynamic‐jaw mode (HDJ) for multiple targets. In the pDJDC plans, we used a beam set with 2–7 ports to the targets at the same level in the craniocaudal direction, and employed another beam set for other targets using different port angles (9–12 angles in total). METHODS: In seven patients, two plans using the pDJDC and HDJ techniques were compared. For multiple targets (n = 2–6), 20–60 Gy in 2‐ to 7.5‐Gy fractions were prescribed for the planning target volumes at D50%. The conformity index, uniformity index (D5%/D95%), dose distribution in the lung, and treatment time were evaluated. RESULTS: The median conformity index of all seven patients was 3.0 for the pDJDC plans and 2.4 for the HDJ plans (P = 0.031). The median uniformity indices of the planning target volume (n = 25) for the two plans were 1.048 and 1.057, respectively (P = 0.10). For five patients with thoracic targets, the median mean lung doses were 2.6 Gy and 2.4 Gy, respectively (P = 0.63). The median V5Gy and V20Gy of the lungs in the five patients were 11.8% and 8.5% (P = 0.63), and 1.6% and 2.1% (P = 0.31), respectively. The pDJDC plans reduced the treatment time by 48% compared to the HDJ plans (median: 462 and 884 sec, respectively, P = 0.031). CONCLUSION: The pDJDC technique allows treatment of multiple targets in almost half the time of the HDJ technique. The pDJDC plans were comparable to the HDJ plans in dose distribution, although the conformity index deteriorated. John Wiley and Sons Inc. 2020-04-06 /pmc/articles/PMC7324698/ /pubmed/32250015 http://dx.doi.org/10.1002/acm2.12874 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Manabe, Yoshihiko
Shibamoto, Yuta
Murai, Taro
Torii, Akira
Niwa, Masanari
Kondo, Takuhito
Okazaki, Dai
Sugie, Chikao
Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles
title Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles
title_full Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles
title_fullStr Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles
title_full_unstemmed Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles
title_short Intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles
title_sort intensity‐modulated radiation therapy for multiple targets with tomotherapy using multiple sets of static ports from different angles
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324698/
https://www.ncbi.nlm.nih.gov/pubmed/32250015
http://dx.doi.org/10.1002/acm2.12874
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