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Thrombospondin-4 induces prolongation of action potential duration in rat isolated ventricular myocytes

Expression of thrombospondin-4 (TSP-4), a matricellular protein, is increased in the heart tissue of various cardiac disease models. In dorsal root ganglion neurons, TSP-4 inhibits L-type Ca(2+) channel (LTCC) activity. Although TSP-4 might be related to the electrophysiological properties in heart,...

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Detalles Bibliográficos
Autores principales:	IMOTO, Keisuke, ARATANI, Momoko, KOYAMA, Takahiro, OKADA, Muneyoshi, YAMAWAKI, Hideyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Veterinary Science 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324826/ https://www.ncbi.nlm.nih.gov/pubmed/32249254 http://dx.doi.org/10.1292/jvms.20-0038

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