The effect of Insulin Degludec on glycemic control in diabetic cats over a 12-month period

Insulin degludec (IDeg) is a long-acting basal insulin recently developed for use in humans. This study aimed to investigate the effects of IDeg on glycemic control in diabetic cats. Changes in body weight, IDeg dosage, and glycated albumin (GA) were evaluated at 0, 1, 3, 6, 9, and 12 months followi...

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Autores principales: ODA, Hitomi, MORI, Akihiro, SAKO, Toshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2020
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324837/
https://www.ncbi.nlm.nih.gov/pubmed/32307342
http://dx.doi.org/10.1292/jvms.19-0309
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author ODA, Hitomi
MORI, Akihiro
SAKO, Toshinori
author_facet ODA, Hitomi
MORI, Akihiro
SAKO, Toshinori
author_sort ODA, Hitomi
collection PubMed
description Insulin degludec (IDeg) is a long-acting basal insulin recently developed for use in humans. This study aimed to investigate the effects of IDeg on glycemic control in diabetic cats. Changes in body weight, IDeg dosage, and glycated albumin (GA) were evaluated at 0, 1, 3, 6, 9, and 12 months following initiation of IDeg. A significant decrease in GA was observed and a mean GA level below 25% was achieved between 3 and 12 months. Furthermore, a significant increase in body weight was observed between 3 and 12 months. The mean IDeg dose was 0.75 ± 0.68 IU/kg/day at 12 months. Taken together, long-term glycemic control was successfully achieved in diabetic cats using IDeg.
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spelling pubmed-73248372020-07-02 The effect of Insulin Degludec on glycemic control in diabetic cats over a 12-month period ODA, Hitomi MORI, Akihiro SAKO, Toshinori J Vet Med Sci Internal Medicine Insulin degludec (IDeg) is a long-acting basal insulin recently developed for use in humans. This study aimed to investigate the effects of IDeg on glycemic control in diabetic cats. Changes in body weight, IDeg dosage, and glycated albumin (GA) were evaluated at 0, 1, 3, 6, 9, and 12 months following initiation of IDeg. A significant decrease in GA was observed and a mean GA level below 25% was achieved between 3 and 12 months. Furthermore, a significant increase in body weight was observed between 3 and 12 months. The mean IDeg dose was 0.75 ± 0.68 IU/kg/day at 12 months. Taken together, long-term glycemic control was successfully achieved in diabetic cats using IDeg. The Japanese Society of Veterinary Science 2020-04-20 2020-06 /pmc/articles/PMC7324837/ /pubmed/32307342 http://dx.doi.org/10.1292/jvms.19-0309 Text en ©2020 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Internal Medicine
ODA, Hitomi
MORI, Akihiro
SAKO, Toshinori
The effect of Insulin Degludec on glycemic control in diabetic cats over a 12-month period
title The effect of Insulin Degludec on glycemic control in diabetic cats over a 12-month period
title_full The effect of Insulin Degludec on glycemic control in diabetic cats over a 12-month period
title_fullStr The effect of Insulin Degludec on glycemic control in diabetic cats over a 12-month period
title_full_unstemmed The effect of Insulin Degludec on glycemic control in diabetic cats over a 12-month period
title_short The effect of Insulin Degludec on glycemic control in diabetic cats over a 12-month period
title_sort effect of insulin degludec on glycemic control in diabetic cats over a 12-month period
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324837/
https://www.ncbi.nlm.nih.gov/pubmed/32307342
http://dx.doi.org/10.1292/jvms.19-0309
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