CB(1) Cannabinoid Receptors Stimulate Gβγ-GRK2-Mediated FAK Phosphorylation at Tyrosine 925 to Regulate ERK Activation Involving Neuronal Focal Adhesions

CB(1) cannabinoid receptors (CB(1)) are abundantly expressed in the nervous system where they regulate focal adhesion kinase (FAK) and the mitogen-activated protein kinases (MAPK) extracellular signal-regulated kinase 1 and 2 (ERK1/2). However, the role of CB(1)-stimulated FAK 925 tyrosine phosphory...

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Detalles Bibliográficos
Autores principales: Dalton, George D., Carney, Skyla T., Marshburn, Jamie D., Norford, Derek C., Howlett, Allyn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324865/
https://www.ncbi.nlm.nih.gov/pubmed/32655375
http://dx.doi.org/10.3389/fncel.2020.00176

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