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Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine’s Biological Activity

[Image: see text] Innovative discovery strategies are essential to address the ongoing opioid epidemic in the United States. Misuse of prescription and illegal opioids (e.g., morphine, heroin) has led to major problems with addiction and overdose. We used vincamine, an indole alkaloid, as a syntheti...

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Detalles Bibliográficos
Autores principales:	Norwood, Verrill M., Brice-Tutt, Ariana C., Eans, Shainnel O., Stacy, Heather M., Shi, Guqin, Ratnayake, Ranjala, Rocca, James R., Abboud, Khalil A., Li, Chenglong, Luesch, Hendrik, McLaughlin, Jay P., Huigens, Robert W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324933/ https://www.ncbi.nlm.nih.gov/pubmed/31913038 http://dx.doi.org/10.1021/acs.jmedchem.9b01924

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