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Development of a Conformational Histamine H(3) Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists

[Image: see text] The histamine H(3) receptor (H(3)R) represents a highly attractive drug target for the treatment of various central nervous system disorders, but the discovery of novel H(3)R targeting compounds relies on the assessment of highly amplified intracellular signaling events that do not...

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Detalles Bibliográficos
Autores principales:	Schihada, Hannes, Ma, Xiaoyuan, Zabel, Ulrike, Vischer, Henry F., Schulte, Gunnar, Leurs, Rob, Pockes, Steffen, Lohse, Martin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325232/ https://www.ncbi.nlm.nih.gov/pubmed/32397705 http://dx.doi.org/10.1021/acssensors.0c00397

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