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Role of DNA repair defects in predicting immunotherapy response

Defect in DNA damage response (DDR) is a common feature of cancer cells, which regulates tumor growth and therapeutic response. Recently, the approval of immune checkpoint blockade (ICB) for tumors with defective mismatch repair has paved the way for investigating the role of other DDR defects in se...

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Detalles Bibliográficos
Autores principales:	Zhang, Jing, Shih, David J. H., Lin, Shiaw-Yih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325270/ https://www.ncbi.nlm.nih.gov/pubmed/32612833 http://dx.doi.org/10.1186/s40364-020-00202-7

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