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Metastatic Malignant Melanoma Mimicking Mammary Mass: A Rare Presentation
Breast lump in perimenopausal women is considered a primary malignancy unless proved otherwise. Metastasis to the breast from extramammary sites is rare. Malignant melanoma (MM) is known for its ability to spread to distant sites, which can be both hematogenous and lymphatic. The common sites are sk...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325399/ https://www.ncbi.nlm.nih.gov/pubmed/32617227 http://dx.doi.org/10.7759/cureus.8354 |
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author | Jain, Ankit Vijayakumar, Chellappa Kumbhar, Uday Sundaramurthi, Sudharsanan Balasubramanian, Gopal |
author_facet | Jain, Ankit Vijayakumar, Chellappa Kumbhar, Uday Sundaramurthi, Sudharsanan Balasubramanian, Gopal |
author_sort | Jain, Ankit |
collection | PubMed |
description | Breast lump in perimenopausal women is considered a primary malignancy unless proved otherwise. Metastasis to the breast from extramammary sites is rare. Malignant melanoma (MM) is known for its ability to spread to distant sites, which can be both hematogenous and lymphatic. The common sites are skin, lung, liver, brain, etc. However, reports of melanoma metastasizing to the breast are rare. We present a case of 50-year-old female patient, who underwent wide local excision and split skin grafting for MM right leg. She did not undergo any adjuvant therapy and one year later presented to us with a solitary lump occupying the upper inner quadrant of the right breast. The breast lump turned out to be metastatic deposit from MM based on the presence of melanin in cells on fine needle aspiration cytology (FNAC). Therefore, breast lump in perimenopausal is not always a primary malignancy, and differential diagnosis should also include metastatic tumors. |
format | Online Article Text |
id | pubmed-7325399 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-73253992020-07-01 Metastatic Malignant Melanoma Mimicking Mammary Mass: A Rare Presentation Jain, Ankit Vijayakumar, Chellappa Kumbhar, Uday Sundaramurthi, Sudharsanan Balasubramanian, Gopal Cureus Pathology Breast lump in perimenopausal women is considered a primary malignancy unless proved otherwise. Metastasis to the breast from extramammary sites is rare. Malignant melanoma (MM) is known for its ability to spread to distant sites, which can be both hematogenous and lymphatic. The common sites are skin, lung, liver, brain, etc. However, reports of melanoma metastasizing to the breast are rare. We present a case of 50-year-old female patient, who underwent wide local excision and split skin grafting for MM right leg. She did not undergo any adjuvant therapy and one year later presented to us with a solitary lump occupying the upper inner quadrant of the right breast. The breast lump turned out to be metastatic deposit from MM based on the presence of melanin in cells on fine needle aspiration cytology (FNAC). Therefore, breast lump in perimenopausal is not always a primary malignancy, and differential diagnosis should also include metastatic tumors. Cureus 2020-05-29 /pmc/articles/PMC7325399/ /pubmed/32617227 http://dx.doi.org/10.7759/cureus.8354 Text en Copyright © 2020, Jain et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pathology Jain, Ankit Vijayakumar, Chellappa Kumbhar, Uday Sundaramurthi, Sudharsanan Balasubramanian, Gopal Metastatic Malignant Melanoma Mimicking Mammary Mass: A Rare Presentation |
title | Metastatic Malignant Melanoma Mimicking Mammary Mass: A Rare Presentation |
title_full | Metastatic Malignant Melanoma Mimicking Mammary Mass: A Rare Presentation |
title_fullStr | Metastatic Malignant Melanoma Mimicking Mammary Mass: A Rare Presentation |
title_full_unstemmed | Metastatic Malignant Melanoma Mimicking Mammary Mass: A Rare Presentation |
title_short | Metastatic Malignant Melanoma Mimicking Mammary Mass: A Rare Presentation |
title_sort | metastatic malignant melanoma mimicking mammary mass: a rare presentation |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325399/ https://www.ncbi.nlm.nih.gov/pubmed/32617227 http://dx.doi.org/10.7759/cureus.8354 |
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