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Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics

Fluorescence imaging in the second near infrared window (NIR-II, 1,000–1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)—a novel kind of NIR-I...

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Detalles Bibliográficos
Autores principales: Yu, Zhenfeng, Eich, Christina, Cruz, Luis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325968/
https://www.ncbi.nlm.nih.gov/pubmed/32656181
http://dx.doi.org/10.3389/fchem.2020.00496
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author Yu, Zhenfeng
Eich, Christina
Cruz, Luis J.
author_facet Yu, Zhenfeng
Eich, Christina
Cruz, Luis J.
author_sort Yu, Zhenfeng
collection PubMed
description Fluorescence imaging in the second near infrared window (NIR-II, 1,000–1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)—a novel kind of NIR-II nanoprobes—are presented. The main focus of this study is on the modification of RENPs and their applications in NIR-II in vitro and in vivo imaging and cancer theranostics. Finally, the perspectives and challenges of NIR-II RENPs are discussed.
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spelling pubmed-73259682020-07-09 Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics Yu, Zhenfeng Eich, Christina Cruz, Luis J. Front Chem Chemistry Fluorescence imaging in the second near infrared window (NIR-II, 1,000–1,700 nm) has been widely used in cancer diagnosis and treatment due to its high spatial resolution and deep tissue penetration depths. In this work, recent advances in rare-earth-doped nanoparticles (RENPs)—a novel kind of NIR-II nanoprobes—are presented. The main focus of this study is on the modification of RENPs and their applications in NIR-II in vitro and in vivo imaging and cancer theranostics. Finally, the perspectives and challenges of NIR-II RENPs are discussed. Frontiers Media S.A. 2020-06-17 /pmc/articles/PMC7325968/ /pubmed/32656181 http://dx.doi.org/10.3389/fchem.2020.00496 Text en Copyright © 2020 Yu, Eich and Cruz. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Yu, Zhenfeng
Eich, Christina
Cruz, Luis J.
Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics
title Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics
title_full Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics
title_fullStr Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics
title_full_unstemmed Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics
title_short Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics
title_sort recent advances in rare-earth-doped nanoparticles for nir-ii imaging and cancer theranostics
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325968/
https://www.ncbi.nlm.nih.gov/pubmed/32656181
http://dx.doi.org/10.3389/fchem.2020.00496
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