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Sex Differences in Cue Competition Effects With a Conditioned Taste Aversion Preparation

This study aimed to test whether male and female rats might show differences in cue competition effects in a conditioned taste aversion (CTA) model. Experiment 1 tested for sex differences in overshadowing. After conditioning of a flavored compound AB or only one simple flavor A (being A and B a sol...

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Autores principales: Angulo, Rocio, Bustamante, Javier, Estades, Vania, Ramírez, Valeska, Jorquera, Belén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325977/
https://www.ncbi.nlm.nih.gov/pubmed/32655385
http://dx.doi.org/10.3389/fnbeh.2020.00107
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author Angulo, Rocio
Bustamante, Javier
Estades, Vania
Ramírez, Valeska
Jorquera, Belén
author_facet Angulo, Rocio
Bustamante, Javier
Estades, Vania
Ramírez, Valeska
Jorquera, Belén
author_sort Angulo, Rocio
collection PubMed
description This study aimed to test whether male and female rats might show differences in cue competition effects in a conditioned taste aversion (CTA) model. Experiment 1 tested for sex differences in overshadowing. After conditioning of a flavored compound AB or only one simple flavor A (being A and B a solution of sugar 10% and salt 1%, counterbalanced), consumption of the A solution at test was larger in the former than in the latter case only in males. Thus, the usual effect of overshadowing was observed in males but not in females. Experiment 2 examined sex differences in blocking with the same stimuli used in Experiment 1. After conditioning of AB, the consumption of B was larger for the animals that previously received a single conditioning trial with A than for those that received unpaired presentations of A and the illness. As observed in Experiment 1, the typical blocking effect appeared only in males but not in females. The present findings thus support the hypothesis that sex dimorphism might be expressed in classical conditioning, or at least, in cue competition effects such as overshadowing and blocking with a taste aversion model.
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spelling pubmed-73259772020-07-09 Sex Differences in Cue Competition Effects With a Conditioned Taste Aversion Preparation Angulo, Rocio Bustamante, Javier Estades, Vania Ramírez, Valeska Jorquera, Belén Front Behav Neurosci Behavioral Neuroscience This study aimed to test whether male and female rats might show differences in cue competition effects in a conditioned taste aversion (CTA) model. Experiment 1 tested for sex differences in overshadowing. After conditioning of a flavored compound AB or only one simple flavor A (being A and B a solution of sugar 10% and salt 1%, counterbalanced), consumption of the A solution at test was larger in the former than in the latter case only in males. Thus, the usual effect of overshadowing was observed in males but not in females. Experiment 2 examined sex differences in blocking with the same stimuli used in Experiment 1. After conditioning of AB, the consumption of B was larger for the animals that previously received a single conditioning trial with A than for those that received unpaired presentations of A and the illness. As observed in Experiment 1, the typical blocking effect appeared only in males but not in females. The present findings thus support the hypothesis that sex dimorphism might be expressed in classical conditioning, or at least, in cue competition effects such as overshadowing and blocking with a taste aversion model. Frontiers Media S.A. 2020-06-22 /pmc/articles/PMC7325977/ /pubmed/32655385 http://dx.doi.org/10.3389/fnbeh.2020.00107 Text en Copyright © 2020 Angulo, Bustamante, Estades, Ramírez and Jorquera. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Behavioral Neuroscience
Angulo, Rocio
Bustamante, Javier
Estades, Vania
Ramírez, Valeska
Jorquera, Belén
Sex Differences in Cue Competition Effects With a Conditioned Taste Aversion Preparation
title Sex Differences in Cue Competition Effects With a Conditioned Taste Aversion Preparation
title_full Sex Differences in Cue Competition Effects With a Conditioned Taste Aversion Preparation
title_fullStr Sex Differences in Cue Competition Effects With a Conditioned Taste Aversion Preparation
title_full_unstemmed Sex Differences in Cue Competition Effects With a Conditioned Taste Aversion Preparation
title_short Sex Differences in Cue Competition Effects With a Conditioned Taste Aversion Preparation
title_sort sex differences in cue competition effects with a conditioned taste aversion preparation
topic Behavioral Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325977/
https://www.ncbi.nlm.nih.gov/pubmed/32655385
http://dx.doi.org/10.3389/fnbeh.2020.00107
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