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A Human 2D Primary Organoid-Derived Epithelial Monolayer Model to Study Host-Pathogen Interaction in the Small Intestine

Gut organoids are stem cell derived 3D models of the intestinal epithelium that are useful for studying interactions between enteric pathogens and their host. While the organoid model has been used for both bacterial and viral infections, this is a closed system with the luminal side being inaccessi...

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Detalles Bibliográficos
Autores principales: Roodsant, Thomas, Navis, Marit, Aknouch, Ikrame, Renes, Ingrid B., van Elburg, Ruurd M., Pajkrt, Dasja, Wolthers, Katja C., Schultsz, Constance, van der Ark, Kees C. H., Sridhar, Adithya, Muncan, Vanesa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326037/
https://www.ncbi.nlm.nih.gov/pubmed/32656095
http://dx.doi.org/10.3389/fcimb.2020.00272