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In vitro Neo-Genesis of Tendon/Ligament-Like Tissue by Combination of Mohawk and a Three-Dimensional Cyclic Mechanical Stretch Culture System
Tendons and ligaments are pivotal connective tissues that tightly connect muscle and bone. In this study, we developed a novel approach to generate tendon/ligament-like tissues with a hierarchical structure, by introducing the tendon/ligament-specific transcription factor Mohawk (MKX) into the mesen...
Autores principales: | Kataoka, Kensuke, Kurimoto, Ryota, Tsutsumi, Hiroki, Chiba, Tomoki, Kato, Tomomi, Shishido, Kana, Kato, Mariko, Ito, Yoshiaki, Cho, Yuichiro, Hoshi, Osamu, Mimata, Ayako, Sakamaki, Yuriko, Nakamichi, Ryo, Lotz, Martin K., Naruse, Keiji, Asahara, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326056/ https://www.ncbi.nlm.nih.gov/pubmed/32671057 http://dx.doi.org/10.3389/fcell.2020.00307 |
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