Distribution of de novo Donor-Specific Antibody Subclasses Quantified by Mass Spectrometry: High IgG3 Proportion Is Associated With Antibody-Mediated Rejection Occurrence and Severity

Donor-specific antibodies (DSAs) are the main risk factor for antibody-mediated rejection (ABMR) and graft loss but could have variable pathogenicity according to their IgG subclass composition. Luminex-based test might lack sensitivity for the detection of IgG subclasses and this test does not allo...

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Detalles Bibliográficos
Autores principales: Pernin, Vincent, Beyze, Anais, Szwarc, Ilan, Bec, Nicole, Salsac, Céline, Perez-Garcia, Esther, Mourad, Georges, Merville, Pierre, Visentin, Jonathan, Perrochia, Helene, Larroque, Christian, Couzi, Lionel, Le Quintrec, Moglie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326073/
https://www.ncbi.nlm.nih.gov/pubmed/32670261
http://dx.doi.org/10.3389/fimmu.2020.00919

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