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Sodium–calcium exchanger 1 is the key molecule for urinary potassium excretion against acute hyperkalemia

The sodium (Na(+))-chloride cotransporter (NCC) expressed in the distal convoluted tubule (DCT) is a key molecule regulating urinary Na(+) and potassium (K(+)) excretion. We previously reported that high-K(+) load rapidly dephosphorylated NCC and promoted urinary K(+) excretion in mouse kidneys. Thi...

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Detalles Bibliográficos
Autores principales: Shoda, Wakana, Nomura, Naohiro, Ando, Fumiaki, Tagashira, Hideaki, Iwamoto, Takahiro, Ohta, Akihito, Isobe, Kiyoshi, Mori, Takayasu, Susa, Koichiro, Sohara, Eisei, Rai, Tatemitsu, Uchida, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326190/
https://www.ncbi.nlm.nih.gov/pubmed/32603346
http://dx.doi.org/10.1371/journal.pone.0235360