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Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass
Osteoporosis is a genetic disease characterized by progressive reductions in bone mineral density (BMD) leading to an increased risk of fracture. Over the last decade, genome-wide association studies (GWASs) have identified over 1000 associations for BMD. However, as a phenotype BMD is challenging a...
Autores principales: | Doolittle, Madison L., Calabrese, Gina M., Mesner, Larry D., Godfrey, Dana A., Maynard, Robert D., Ackert-Bicknell, Cheryl L., Farber, Charles R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326283/ https://www.ncbi.nlm.nih.gov/pubmed/32497039 http://dx.doi.org/10.1371/journal.pgen.1008805 |
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