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Activation of Notch1 signaling in podocytes by glucose-derived AGEs contributes to proteinuria

INTRODUCTION: Advanced glycation end-products (AGEs) are implicated in the pathogenesis of diabetic nephropathy (DN). Previous studies have shown that AGEs contribute to glomerulosclerosis and proteinuria. Podocytes, terminally differentiated epithelial cells of the glomerulus and the critical compo...

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Detalles Bibliográficos
Autores principales:	Nishad, Rajkishor, Meshram, Prajakta, Singh, Ashish Kumar, Reddy, G Bhanuprakash, Pasupulati, Anil Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Pathophysiology/Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326296/ https://www.ncbi.nlm.nih.gov/pubmed/32601154 http://dx.doi.org/10.1136/bmjdrc-2020-001203

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