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Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound?
For the first 3 months of COVID-19 pandemic, COVID-19 was expected to be an immunizing non-relapsing disease. We report a national case series of 11 virologically-confirmed COVID-19 patients having experienced a second clinically- and virologically-confirmed acute COVID-19 episode. According to the...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Infection Association. Published by Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326402/ https://www.ncbi.nlm.nih.gov/pubmed/32619697 http://dx.doi.org/10.1016/j.jinf.2020.06.073 |
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author | Gousseff, Marie Penot, Pauline Gallay, Laure Batisse, Dominique Benech, Nicolas Bouiller, Kevin Collarino, Rocco Conrad, Anne Slama, Dorsaf Joseph, Cédric Lemaignen, Adrien Lescure, François-Xavier Levy, Bruno Mahevas, Matthieu Pozzetto, Bruno Vignier, Nicolas Wyplosz, Benjamin Salmon, Dominique Goehringer, Francois Botelho-Nevers, Elisabeth |
author_facet | Gousseff, Marie Penot, Pauline Gallay, Laure Batisse, Dominique Benech, Nicolas Bouiller, Kevin Collarino, Rocco Conrad, Anne Slama, Dorsaf Joseph, Cédric Lemaignen, Adrien Lescure, François-Xavier Levy, Bruno Mahevas, Matthieu Pozzetto, Bruno Vignier, Nicolas Wyplosz, Benjamin Salmon, Dominique Goehringer, Francois Botelho-Nevers, Elisabeth |
author_sort | Gousseff, Marie |
collection | PubMed |
description | For the first 3 months of COVID-19 pandemic, COVID-19 was expected to be an immunizing non-relapsing disease. We report a national case series of 11 virologically-confirmed COVID-19 patients having experienced a second clinically- and virologically-confirmed acute COVID-19 episode. According to the clinical history, we discuss either re-infection or reactivation hypothesis. Larger studies including further virological, immunological and epidemiologic data are needed to understand the mechanisms of these recurrences. |
format | Online Article Text |
id | pubmed-7326402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The British Infection Association. Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73264022020-07-01 Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound? Gousseff, Marie Penot, Pauline Gallay, Laure Batisse, Dominique Benech, Nicolas Bouiller, Kevin Collarino, Rocco Conrad, Anne Slama, Dorsaf Joseph, Cédric Lemaignen, Adrien Lescure, François-Xavier Levy, Bruno Mahevas, Matthieu Pozzetto, Bruno Vignier, Nicolas Wyplosz, Benjamin Salmon, Dominique Goehringer, Francois Botelho-Nevers, Elisabeth J Infect Letter to the Editor For the first 3 months of COVID-19 pandemic, COVID-19 was expected to be an immunizing non-relapsing disease. We report a national case series of 11 virologically-confirmed COVID-19 patients having experienced a second clinically- and virologically-confirmed acute COVID-19 episode. According to the clinical history, we discuss either re-infection or reactivation hypothesis. Larger studies including further virological, immunological and epidemiologic data are needed to understand the mechanisms of these recurrences. The British Infection Association. Published by Elsevier Ltd. 2020-11 2020-06-30 /pmc/articles/PMC7326402/ /pubmed/32619697 http://dx.doi.org/10.1016/j.jinf.2020.06.073 Text en © 2020 The British Infection Association. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Letter to the Editor Gousseff, Marie Penot, Pauline Gallay, Laure Batisse, Dominique Benech, Nicolas Bouiller, Kevin Collarino, Rocco Conrad, Anne Slama, Dorsaf Joseph, Cédric Lemaignen, Adrien Lescure, François-Xavier Levy, Bruno Mahevas, Matthieu Pozzetto, Bruno Vignier, Nicolas Wyplosz, Benjamin Salmon, Dominique Goehringer, Francois Botelho-Nevers, Elisabeth Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound? |
title | Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound? |
title_full | Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound? |
title_fullStr | Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound? |
title_full_unstemmed | Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound? |
title_short | Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound? |
title_sort | clinical recurrences of covid-19 symptoms after recovery: viral relapse, reinfection or inflammatory rebound? |
topic | Letter to the Editor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326402/ https://www.ncbi.nlm.nih.gov/pubmed/32619697 http://dx.doi.org/10.1016/j.jinf.2020.06.073 |
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