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Landscape of Non-canonical Cysteines in Human V(H) Repertoire Revealed by Immunogenetic Analysis
Human antibody repertoire data captured through next-generation sequencing (NGS) has enabled deeper insights into B cell immunogenetics and paratope diversity. By analyzing large public NGS datasets, we map the landscape of non-canonical cysteines in human variable heavy-chain domains (V(H)s) at the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s).
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326410/ https://www.ncbi.nlm.nih.gov/pubmed/32610132 http://dx.doi.org/10.1016/j.celrep.2020.107831 |