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Tamarix arabica and Salvadora persica as antibacterial agents
Despite the harsh conditions and limited water resources of the Arabian Peninsula, plants that live in this environment contain a variety of bioactive compounds and have been used in traditional medicines for thousands of years. We investigated the effects of ethanol extracts of Tamarix arabica and...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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AIMS Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326732/ https://www.ncbi.nlm.nih.gov/pubmed/32617445 http://dx.doi.org/10.3934/microbiol.2020008 |
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author | Al-Judaibi, Awatif A. |
author_facet | Al-Judaibi, Awatif A. |
author_sort | Al-Judaibi, Awatif A. |
collection | PubMed |
description | Despite the harsh conditions and limited water resources of the Arabian Peninsula, plants that live in this environment contain a variety of bioactive compounds and have been used in traditional medicines for thousands of years. We investigated the effects of ethanol extracts of Tamarix arabica and Salvadora persica on Gram-negative and Gram-positive bacteria. The investigations were include; the inhibition of the bacterial growth, determination of MIC and MBC, detection of kill-time, potassium and phosphorus leakages and detection of the bioactive compounds by the GC-MS analysis. The tested extracts in combination, at a 1:1 volume ratio, showed high inhibitory effects, as reflected by the minimum inhibitory concentrations and minimum bactericidal concentrations. The new EC plate was used to determined MBC and kill-time. Further, the detection of phosphate and potassium leakage indicated a loss of selective permeability of the cytoplasmic membrane after treatment with these extracts. The bioactive compounds in the ethanol extracts of T. arabica and S. persica may offer a less expensive and natural alternative to pharmaceuticals. |
format | Online Article Text |
id | pubmed-7326732 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | AIMS Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-73267322020-07-01 Tamarix arabica and Salvadora persica as antibacterial agents Al-Judaibi, Awatif A. AIMS Microbiol Research Article Despite the harsh conditions and limited water resources of the Arabian Peninsula, plants that live in this environment contain a variety of bioactive compounds and have been used in traditional medicines for thousands of years. We investigated the effects of ethanol extracts of Tamarix arabica and Salvadora persica on Gram-negative and Gram-positive bacteria. The investigations were include; the inhibition of the bacterial growth, determination of MIC and MBC, detection of kill-time, potassium and phosphorus leakages and detection of the bioactive compounds by the GC-MS analysis. The tested extracts in combination, at a 1:1 volume ratio, showed high inhibitory effects, as reflected by the minimum inhibitory concentrations and minimum bactericidal concentrations. The new EC plate was used to determined MBC and kill-time. Further, the detection of phosphate and potassium leakage indicated a loss of selective permeability of the cytoplasmic membrane after treatment with these extracts. The bioactive compounds in the ethanol extracts of T. arabica and S. persica may offer a less expensive and natural alternative to pharmaceuticals. AIMS Press 2020-05-18 /pmc/articles/PMC7326732/ /pubmed/32617445 http://dx.doi.org/10.3934/microbiol.2020008 Text en © 2020 the Author(s), licensee AIMS Press This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) |
spellingShingle | Research Article Al-Judaibi, Awatif A. Tamarix arabica and Salvadora persica as antibacterial agents |
title | Tamarix arabica and Salvadora persica as antibacterial agents |
title_full | Tamarix arabica and Salvadora persica as antibacterial agents |
title_fullStr | Tamarix arabica and Salvadora persica as antibacterial agents |
title_full_unstemmed | Tamarix arabica and Salvadora persica as antibacterial agents |
title_short | Tamarix arabica and Salvadora persica as antibacterial agents |
title_sort | tamarix arabica and salvadora persica as antibacterial agents |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326732/ https://www.ncbi.nlm.nih.gov/pubmed/32617445 http://dx.doi.org/10.3934/microbiol.2020008 |
work_keys_str_mv | AT aljudaibiawatifa tamarixarabicaandsalvadorapersicaasantibacterialagents |