Identification of Unique mRNA and miRNA Expression Patterns in Bone Marrow Hematopoietic Stem and Progenitor Cells After Trauma in Older Adults

Older adults have significantly worse morbidity and mortality after severe trauma than younger cohorts. The competency of the innate immune response decreases with advancing age, especially after an inflammatory insult. Subsequent poor outcomes after trauma are caused in part by dysfunctional leukoc...

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Detalles Bibliográficos
Autores principales: Darden, Dijoia B., Stortz, Julie A., Hollen, McKenzie K., Cox, Michael C., Apple, Camille G., Hawkins, Russell B., Rincon, Jaimar C., Lopez, Maria-Cecilia, Wang, Zhongkai, Navarro, Eduardo, Hagen, Jennifer E., Parvataneni, Hari K., Brusko, Maigan A., Kladde, Michael, Bacher, Rhonda, Brumback, Babette A., Brakenridge, Scott C., Baker, Henry V., Cogle, Christopher R., Mohr, Alicia M., Efron, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326804/
https://www.ncbi.nlm.nih.gov/pubmed/32670283
http://dx.doi.org/10.3389/fimmu.2020.01289

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