Hypoxanthine-Guanine Phosphoribosyltransferase/adenylate Kinase From Zobellia galactanivorans: A Bifunctional Catalyst for the Synthesis of Nucleoside-5′-Mono-, Di- and Triphosphates

In our search for novel biocatalysts for the synthesis of nucleic acid derivatives, we found a good candidate in a putative dual-domain hypoxanthine-guanine phosphoribosyltransferase (HGPRT)/adenylate kinase (AMPK) from Zobellia galactanivorans (ZgHGPRT/AMPK). In this respect, we report for the firs...

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Detalles Bibliográficos
Autores principales: Acosta, Javier, Del Arco, Jon, Del Pozo, Maria Luisa, Herrera-Tapias, Beliña, Clemente-Suárez, Vicente Javier, Berenguer, José, Hidalgo, Aurelio, Fernández-Lucas, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326950/
https://www.ncbi.nlm.nih.gov/pubmed/32671046
http://dx.doi.org/10.3389/fbioe.2020.00677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326950/
https://www.ncbi.nlm.nih.gov/pubmed/32671046
http://dx.doi.org/10.3389/fbioe.2020.00677

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