A severe refractory COVID-19 patient responding to convalescent plasma; A case series

INTRODUCTION: Although some medicines are under research, currently, no specific antiviral drug has been approved to target 2019 novel coronavirus. In this report two severe cases of 2019 novel coronavirus disease (COVID-19) patients have been described who received convalescent plasma (CP). CASE RE...

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Autores principales: Abdullah, Hadi Mohammed, Hama-Ali, Hersh H., Ahmed, Sabah Nasraddin, Ali, Kosar Muhammad, Karadakhy, Kamaran Amin, Mahmood, Safeen Othman, Mahmood, Zana Hameed, Hamad Amin, Karmand Qadir, Atta, Peshnyar Muhammad, Nuradeen, Bryar Ezadeen, Mohammed, Shvan H., Salih, Rawezh Q., Baba, Hiwa O., Kakamad, Fahmi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327024/
https://www.ncbi.nlm.nih.gov/pubmed/32637086
http://dx.doi.org/10.1016/j.amsu.2020.06.018
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author Abdullah, Hadi Mohammed
Hama-Ali, Hersh H.
Ahmed, Sabah Nasraddin
Ali, Kosar Muhammad
Karadakhy, Kamaran Amin
Mahmood, Safeen Othman
Mahmood, Zana Hameed
Hamad Amin, Karmand Qadir
Atta, Peshnyar Muhammad
Nuradeen, Bryar Ezadeen
Mohammed, Shvan H.
Salih, Rawezh Q.
Baba, Hiwa O.
Kakamad, Fahmi H.
author_facet Abdullah, Hadi Mohammed
Hama-Ali, Hersh H.
Ahmed, Sabah Nasraddin
Ali, Kosar Muhammad
Karadakhy, Kamaran Amin
Mahmood, Safeen Othman
Mahmood, Zana Hameed
Hamad Amin, Karmand Qadir
Atta, Peshnyar Muhammad
Nuradeen, Bryar Ezadeen
Mohammed, Shvan H.
Salih, Rawezh Q.
Baba, Hiwa O.
Kakamad, Fahmi H.
author_sort Abdullah, Hadi Mohammed
collection PubMed
description INTRODUCTION: Although some medicines are under research, currently, no specific antiviral drug has been approved to target 2019 novel coronavirus. In this report two severe cases of 2019 novel coronavirus disease (COVID-19) patients have been described who received convalescent plasma (CP). CASE REPORT: Two male cases (a 46-year-old and a 56-year-old) after being diagnosed with severe COVID-19, they deteriorated despite supportive care and antiviral therapy. They started to improve with CP infusion both clinically and radiologically. Finally they were discharged in a very well condition with negative virology tests. CONCLUSION: CP might be an effective therapy for severe COVID-19 patients.
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spelling pubmed-73270242020-07-06 A severe refractory COVID-19 patient responding to convalescent plasma; A case series Abdullah, Hadi Mohammed Hama-Ali, Hersh H. Ahmed, Sabah Nasraddin Ali, Kosar Muhammad Karadakhy, Kamaran Amin Mahmood, Safeen Othman Mahmood, Zana Hameed Hamad Amin, Karmand Qadir Atta, Peshnyar Muhammad Nuradeen, Bryar Ezadeen Mohammed, Shvan H. Salih, Rawezh Q. Baba, Hiwa O. Kakamad, Fahmi H. Ann Med Surg (Lond) Original Research INTRODUCTION: Although some medicines are under research, currently, no specific antiviral drug has been approved to target 2019 novel coronavirus. In this report two severe cases of 2019 novel coronavirus disease (COVID-19) patients have been described who received convalescent plasma (CP). CASE REPORT: Two male cases (a 46-year-old and a 56-year-old) after being diagnosed with severe COVID-19, they deteriorated despite supportive care and antiviral therapy. They started to improve with CP infusion both clinically and radiologically. Finally they were discharged in a very well condition with negative virology tests. CONCLUSION: CP might be an effective therapy for severe COVID-19 patients. Elsevier 2020-06-24 /pmc/articles/PMC7327024/ /pubmed/32637086 http://dx.doi.org/10.1016/j.amsu.2020.06.018 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Research
Abdullah, Hadi Mohammed
Hama-Ali, Hersh H.
Ahmed, Sabah Nasraddin
Ali, Kosar Muhammad
Karadakhy, Kamaran Amin
Mahmood, Safeen Othman
Mahmood, Zana Hameed
Hamad Amin, Karmand Qadir
Atta, Peshnyar Muhammad
Nuradeen, Bryar Ezadeen
Mohammed, Shvan H.
Salih, Rawezh Q.
Baba, Hiwa O.
Kakamad, Fahmi H.
A severe refractory COVID-19 patient responding to convalescent plasma; A case series
title A severe refractory COVID-19 patient responding to convalescent plasma; A case series
title_full A severe refractory COVID-19 patient responding to convalescent plasma; A case series
title_fullStr A severe refractory COVID-19 patient responding to convalescent plasma; A case series
title_full_unstemmed A severe refractory COVID-19 patient responding to convalescent plasma; A case series
title_short A severe refractory COVID-19 patient responding to convalescent plasma; A case series
title_sort severe refractory covid-19 patient responding to convalescent plasma; a case series
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327024/
https://www.ncbi.nlm.nih.gov/pubmed/32637086
http://dx.doi.org/10.1016/j.amsu.2020.06.018
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