A novel 4-aminoquinazoline derivative, DHW-208, suppresses the growth of human breast cancer cells by targeting the PI3K/AKT/mTOR pathway

Breast cancer is one of the most frequent cancers among women worldwide. However, there is still no effective therapeutic strategy for advanced breast cancer that has metastasized. Aberrant activation of the PI3K/AKT/mTOR pathway is an essential step for the growth of human breast cancers. In our pr...

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Detalles Bibliográficos
Autores principales: Wang, Shu, Zhang, Yingshi, Ren, Tianshu, Wu, Qiong, Lu, Hongyuan, Qin, Xiaochun, Liu, Yuyan, Ding, Huaiwei, Zhao, Qingchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327080/
https://www.ncbi.nlm.nih.gov/pubmed/32606352
http://dx.doi.org/10.1038/s41419-020-2690-y

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