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Econazole Induces p53-Dependent Apoptosis and Decreases Metastasis Ability in Gastric Cancer Cells

Econazole, a potent broad-spectrum antifungal agent and a Ca(2+) channel antagonist, induces cytotoxicity in leukemia cells and is used for the treatment of skin infections. However, little is known about its cytotoxic effects on solid tumor cells. Here, we investigated the molecular mechanism under...

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Detalles Bibliográficos
Autores principales: Choi, Eun Kyoung, Park, Eun Jung, Phan, Tien Thuy, Kim, Hea Dong, Hoe, Kwang-Lae, Kim, Dong-Uk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327138/
https://www.ncbi.nlm.nih.gov/pubmed/32209732
http://dx.doi.org/10.4062/biomolther.2019.201