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Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds

Trauma-related necrotizing myocutaneous mucormycosis (NMM) has a high morbidity and mortality in victims of combat-related injuries, geometeorological disasters, and severe burns. Inspired by the observation that several recent clusters of NMM have been associated with extreme mechanical forces (e.g...

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Detalles Bibliográficos
Autores principales: Wurster, Sebastian, Tatara, Alexander M., Albert, Nathaniel D., Ibrahim, Ashraf S., Heitman, Joseph, Lee, Soo Chan, Shetty, Amol C., McCracken, Carrie, Graf, Karen T., Mikos, Antonios G., Bruno, Vincent M., Kontoyiannis, Dimitrios P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327176/
https://www.ncbi.nlm.nih.gov/pubmed/32605990
http://dx.doi.org/10.1128/mBio.01414-20

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