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Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds
Trauma-related necrotizing myocutaneous mucormycosis (NMM) has a high morbidity and mortality in victims of combat-related injuries, geometeorological disasters, and severe burns. Inspired by the observation that several recent clusters of NMM have been associated with extreme mechanical forces (e.g...
Autores principales: | Wurster, Sebastian, Tatara, Alexander M., Albert, Nathaniel D., Ibrahim, Ashraf S., Heitman, Joseph, Lee, Soo Chan, Shetty, Amol C., McCracken, Carrie, Graf, Karen T., Mikos, Antonios G., Bruno, Vincent M., Kontoyiannis, Dimitrios P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327176/ https://www.ncbi.nlm.nih.gov/pubmed/32605990 http://dx.doi.org/10.1128/mBio.01414-20 |
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