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Regulation of the miR-19b-mediated SOCS6-JAK2/STAT3 pathway by lncRNA MEG3 is involved in high glucose-induced apoptosis in hRMECs

Objective: Diabetic retinopathy (DR) is one of the most severe and common complications of diabetes mellitus. The present study aimed to investigate the molecular mechanism of MEG3, miR-19b and SOCS6 in human retinal microvascular endothelial cells (hRMECs) under high glucose conditions. Methods: HR...

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Detalles Bibliográficos
Autores principales: Xiao, Fan, Li, Lan, Fu, Jing-Song, Hu, Yu-Xiang, Luo, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327180/
https://www.ncbi.nlm.nih.gov/pubmed/32519748
http://dx.doi.org/10.1042/BSR20194370