Nitrous oxide as a putative novel dual-mechanism treatment for bipolar depression: Proof-of-concept study design and methodology

INTRODUCTION: Depressive symptoms predominate in the course of bipolar disorder (BD) and there is an urgent need to evaluate novel application of repurposed compounds that act on pre-specified treatment targets. Several lines of reasoning suggest that nitrous oxide (N(2)O) is an ideal medication to...

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Detalles Bibliográficos
Autores principales: Dimick, Mikaela K., Omrin, Danielle, MacIntosh, Bradley J., Mitchell, Rachel H.B., Riegert, Daniel, Levitt, Anthony, Schaffer, Ayal, Belo, Susan, Iazzetta, John, Detzler, Garfield, Choi, Mabel, Choi, Stephen, Orser, Beverley A., Goldstein, Benjamin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327241/
https://www.ncbi.nlm.nih.gov/pubmed/32637725
http://dx.doi.org/10.1016/j.conctc.2020.100600

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