Nanoformulation of the superoxide dismutase mimic, MnTnBuOE-2-PyP(5+), prevents its acute hypotensive response

Scavenging superoxide (O(2)(•-)) via overexpression of superoxide dismutase (SOD) or administration of SOD mimics improves outcomes in multiple experimental models of human disease including cardiovascular disease, neurodegeneration, and cancer. While few SOD mimics have transitioned to clinical tri...

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Detalles Bibliográficos
Autores principales: Schlichte, Sarah L., Romanova, Svetlana, Katsurada, Kenichi, Kosmacek, Elizabeth A., Bronich, Tatiana K., Patel, Kaushik P., Oberley-Deegan, Rebecca E., Zimmerman, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327277/
https://www.ncbi.nlm.nih.gov/pubmed/32863236
http://dx.doi.org/10.1016/j.redox.2020.101610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327277/
https://www.ncbi.nlm.nih.gov/pubmed/32863236
http://dx.doi.org/10.1016/j.redox.2020.101610

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