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High-level gain of mesenchymal-epithelial transition factor (MET) copy number using next-generation sequencing as a predictive biomarker for MET inhibitor efficacy

BACKGROUND: In clinical oncology, targeted next-generation sequencing (NGS) has become an integral part of the routine molecular diagnostics repertoire. However, a consensus is yet to be agreed on the optimal mesenchymal-epithelial transition factor (MET) copy number (CN) cut-off value based on NGS...

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Detalles Bibliográficos
Autores principales:	Wu, Shibo, Li, Guodong, Zhao, Xin, Xiang, Jianxing, Lizaso, Analyn, Ye, Junyi, Shi, Chunlei, Chen, Lingxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327325/ https://www.ncbi.nlm.nih.gov/pubmed/32617305 http://dx.doi.org/10.21037/atm-20-2741

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