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Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients
The novel coronavirus infection has spread worldwide, causing a wide spectrum of clinical manifestations. Most patients develop moderate clinical illness, but a substantial number will experience severe pneumonia, which may rapidly progress to acute respiratory distress syndrome and multiple organ f...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327460/ https://www.ncbi.nlm.nih.gov/pubmed/32613288 http://dx.doi.org/10.1007/s40291-020-00481-8 |
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author | Chalkias, Athanasios Mouzarou, Angeliki Samara, Evangelia Xanthos, Theodoros Ischaki, Eleni Pantazopoulos, Ioannis |
author_facet | Chalkias, Athanasios Mouzarou, Angeliki Samara, Evangelia Xanthos, Theodoros Ischaki, Eleni Pantazopoulos, Ioannis |
author_sort | Chalkias, Athanasios |
collection | PubMed |
description | The novel coronavirus infection has spread worldwide, causing a wide spectrum of clinical manifestations. Most patients develop moderate clinical illness, but a substantial number will experience severe pneumonia, which may rapidly progress to acute respiratory distress syndrome and multiple organ failure. In this population, soluble urokinase plasminogen activator receptor (suPAR) could serve as a quick triage test and independent marker of clinical severity, hospital and intensive care unit admission, complications, and mortality. |
format | Online Article Text |
id | pubmed-7327460 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-73274602020-07-01 Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients Chalkias, Athanasios Mouzarou, Angeliki Samara, Evangelia Xanthos, Theodoros Ischaki, Eleni Pantazopoulos, Ioannis Mol Diagn Ther Current Opinion The novel coronavirus infection has spread worldwide, causing a wide spectrum of clinical manifestations. Most patients develop moderate clinical illness, but a substantial number will experience severe pneumonia, which may rapidly progress to acute respiratory distress syndrome and multiple organ failure. In this population, soluble urokinase plasminogen activator receptor (suPAR) could serve as a quick triage test and independent marker of clinical severity, hospital and intensive care unit admission, complications, and mortality. Springer International Publishing 2020-07-01 2020 /pmc/articles/PMC7327460/ /pubmed/32613288 http://dx.doi.org/10.1007/s40291-020-00481-8 Text en © Springer Nature Switzerland AG 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Current Opinion Chalkias, Athanasios Mouzarou, Angeliki Samara, Evangelia Xanthos, Theodoros Ischaki, Eleni Pantazopoulos, Ioannis Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients |
title | Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients |
title_full | Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients |
title_fullStr | Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients |
title_full_unstemmed | Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients |
title_short | Soluble Urokinase Plasminogen Activator Receptor: A Biomarker for Predicting Complications and Critical Care Admission of COVID-19 Patients |
title_sort | soluble urokinase plasminogen activator receptor: a biomarker for predicting complications and critical care admission of covid-19 patients |
topic | Current Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327460/ https://www.ncbi.nlm.nih.gov/pubmed/32613288 http://dx.doi.org/10.1007/s40291-020-00481-8 |
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