Cargando…

Deciphering the regulatory landscape of fetal and adult γδ T‐cell development at single‐cell resolution

γδ T cells with distinct properties develop in the embryonic and adult thymus and have been identified as critical players in a broad range of infections, antitumor surveillance, autoimmune diseases, and tissue homeostasis. Despite their potential value for immunotherapy, differentiation of γδ T cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sagar, , Pokrovskii, Maria, Herman, Josip S, Naik, Shruti, Sock, Elisabeth, Zeis, Patrice, Lausch, Ute, Wegner, Michael, Tanriver, Yakup, Littman, Dan R, Grün, Dominic
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Resources
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327493/ https://www.ncbi.nlm.nih.gov/pubmed/32627520 http://dx.doi.org/10.15252/embj.2019104159

Ejemplares similares

Single-cell RNA-sequencing identifies the developmental trajectory of C-Myc-dependent NK1.1(−) T-bet(+) intraepithelial lymphocyte precursors
por: Hummel, Jonas F., et al.
Publicado: (2019)

Single-cell RNA sequencing of human breast tumour-infiltrating immune cells reveals a γδ T-cell subtype associated with good clinical outcome
por: Boufea, Katerina, et al.
Publicado: (2020)

Deciphering Signatures of Mutational Processes Operative in Human Cancer
por: Alexandrov, Ludmil B., et al.
Publicado: (2013)

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
por: Boer, Cindy G., et al.
Publicado: (2021)

De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data
por: Grün, Dominic, et al.
Publicado: (2016)

Gestationally dependent immune organization at the maternal-fetal interface
por: Moore, Amber R., et al.
Publicado: (2022)

Isolation of Progenitors that Exhibit Myogenic/Osteogenic Bipotency In Vitro by Fluorescence-Activated Cell Sorting from Human Fetal Muscle
por: Castiglioni, Alessandra, et al.
Publicado: (2014)

KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas
por: Roost, Matthias S., et al.
Publicado: (2015)

Deciphering human ribonucleoprotein regulatory networks
por: Mukherjee, Neelanjan, et al.
Publicado: (2019)

Generation of functional human T cell development in NOD/SCID/IL2rγ(null) humanized mice without using fetal tissue: Application as a model of HIV infection and persistence
por: Colas, Chloé, et al.
Publicado: (2023)

Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression
por: Yeo, Alan T., et al.
Publicado: (2022)

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development
por: Hochane, Mazène, et al.
Publicado: (2019)

Human cytomegalovirus elicits fetal γδ T cell responses in utero
por: Vermijlen, David, et al.
Publicado: (2010)

The human fetal thymus generates invariant effector γδ T cells
por: Tieppo, Paola, et al.
Publicado: (2019)

A Human Liver Cell Atlas reveals Heterogeneity and Epithelial Progenitors
por: Aizarani, Nadim, et al.
Publicado: (2019)

Generation of human long-lived plasma cells by developmentally regulated epigenetic imprinting
por: Joyner, Chester J, et al.
Publicado: (2021)

A Flexible Reporter System for Direct Observation and Isolation of Cancer Stem Cells
por: Tang, Binwu, et al.
Publicado: (2014)

CRISPR-Cas9 human gene replacement and phenomic characterization in Caenorhabditis elegans to understand the functional conservation of human genes and decipher variants of uncertain significance
por: McDiarmid, Troy A., et al.
Publicado: (2018)

An Arabidopsis lipid map reveals differences between tissues and dynamic changes throughout development
por: Kehelpannala, Cheka, et al.
Publicado: (2021)

HEB is required for the specification of fetal IL-17-producing γδ T cells
por: In, Tracy S. H., et al.
Publicado: (2017)

Dissecting the transcriptome landscape of the human fetal neural retina and retinal pigment epithelium by single-cell RNA-seq analysis
por: Hu, Yuqiong, et al.
Publicado: (2019)

Response to SARS-CoV-2 vaccines in patients receiving B-cell modulating antibodies for renal autoimmune disease
por: Arnold, Frederic, et al.
Publicado: (2022)

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver
por: Wang, Jingkui, et al.
Publicado: (2017)

A single-cell map of dynamic chromatin landscapes of immune cells in renal cell carcinoma
por: Kourtis, Nikos, et al.
Publicado: (2022)

Pulmonary transcriptome analysis in the surgically induced rabbit model of diaphragmatic hernia treated with fetal tracheal occlusion
por: Engels, Alexander C., et al.
Publicado: (2016)

An Immune Atlas of Clear Cell Renal Cell Carcinoma
por: Chevrier, Stéphane, et al.
Publicado: (2017)

CellCoal: Coalescent Simulation of Single-Cell Sequencing Samples
por: Posada, David
Publicado: (2020)

Tracing the Derivation of Embryonic Stem Cells from the Inner Cell Mass by Single-Cell RNA-Seq Analysis
por: Tang, Fuchou, et al.
Publicado: (2010)

Single-Cell Analysis of Proxy Reporter Allele-Marked Epithelial Cells Establishes Intestinal Stem Cell Hierarchy
por: Li, Ning, et al.
Publicado: (2014)

A single-cell atlas of glioblastoma evolution under therapy reveals cell-intrinsic and cell-extrinsic therapeutic targets
por: Wang, Lin, et al.
Publicado: (2022)

Strong anion exchange‐mediated phosphoproteomics reveals extensive human non‐canonical phosphorylation
por: Hardman, Gemma, et al.
Publicado: (2019)

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution
por: Cowan, Cameron S., et al.
Publicado: (2020)

Single‐cell profiling of muscle‐infiltrating T cells in idiopathic inflammatory myopathies
por: Argyriou, Alexandra, et al.
Publicado: (2023)

Single-cell multiomic analysis of thymocyte development reveals drivers of CD4(+) T cell and CD8(+) T cell lineage commitment
por: Steier, Zoë, et al.
Publicado: (2023)

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome
por: Nica, Alexandra C., et al.
Publicado: (2013)

Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity
por: Garner, Lucy C., et al.
Publicado: (2023)

Cell-Surface Proteomics Identifies Lineage-Specific Markers of Embryo-Derived Stem Cells
por: Rugg-Gunn, Peter J., et al.
Publicado: (2012)

Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells
por: Macaulay, Iain C., et al.
Publicado: (2016)

Single-Cell DNA Methylome Sequencing and Bioinformatic Inference of Epigenomic Cell-State Dynamics
por: Farlik, Matthias, et al.
Publicado: (2015)

Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture
por: Olmer, Ruth, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_th91pa2tchi02eqhkcagl2c0ev